(A, C, E, and G) Huh-7.5 spheroids were incubated with DMSO or 5 μM AG-1478 for 2 hr, infected with DiD-HCV (red) with DMSO or AG-1478 for 1 hr at 4°C, shifted to 37°C for the indicated times, fixed, and probed for ZO-1 (A), CLDN1 (C), clathrin light chain (clathrin LC) (E) or AP-2μ1 (G) (green). (B, D, F, and H) Quantitation of (A), (C), (E) and (G), respectively. n = total DiD signal. Mean +/- SEM. **p < 0.01.</p
Hepatitis C virus (HCV) is a model for the study of virus–host interaction and host cell responses t...
<p>To evaluate the possible routes of HCV infection, the mRNA (A) and protein (B) expression of vari...
International audienceHepatitis C virus (HCV) is a major cause of liver disease, but therapeutic opt...
(A and C) Huh-7.5 spheroids were incubated with DMSO or 5 μM AG-1478 for 2 hr, infected with DiD-HCV...
(A) Huh-7.5 spheroids were incubated with DMSO or 5 μM AG-1478 for 2h, infected with DiD-HCV (red) w...
(A, C, E, and G) Huh-7.5 spheroids were incubated with DMSO or 5 μM sorafenib for 2 hr, infected wit...
(A and C) Spheroids of Huh-7.5 wildtype or OCLN CRISPR’ed cells were infected with DiD-HCV (red) for...
(A and B) Huh-7.5 spheroids were serum starved, incubated with 5 μM AG-1478 (A) or sorafenib (B) for...
(A-F) Huh-7.5 spheroids were incubated with DMSO or 5 μM AG-1478 for 2h, infected with DiD-HCV (red)...
(A) Huh-7.5 wildtype, OCLN CRISPR’ed, or complemented cells were seeded onto 96-well plates, infecte...
<p>For (A) and (B) the hepatoma cell lines Huh7 and Huh7.5 were cultured for 48 hours while primary ...
<p><b>A</b>) ARPE-19 cells were transduced with Ad-tet-trans alone (Normal) or Ad-PDGFRα and Ad-tet-...
<p>The nuclear receptor mediated pathway is activated by E2 and blocked by Tamoxifen (Tam) in most c...
(A) Western blot of Huh-7.5 wildtype, CLDN1 CRISPR’ed, and complemented cells. (B) Huh-7.5 wildtype,...
Le virus de l'hépatite C (HCV) est une cause majeure de maladie chronique du foie et de carcinome hé...
Hepatitis C virus (HCV) is a model for the study of virus–host interaction and host cell responses t...
<p>To evaluate the possible routes of HCV infection, the mRNA (A) and protein (B) expression of vari...
International audienceHepatitis C virus (HCV) is a major cause of liver disease, but therapeutic opt...
(A and C) Huh-7.5 spheroids were incubated with DMSO or 5 μM AG-1478 for 2 hr, infected with DiD-HCV...
(A) Huh-7.5 spheroids were incubated with DMSO or 5 μM AG-1478 for 2h, infected with DiD-HCV (red) w...
(A, C, E, and G) Huh-7.5 spheroids were incubated with DMSO or 5 μM sorafenib for 2 hr, infected wit...
(A and C) Spheroids of Huh-7.5 wildtype or OCLN CRISPR’ed cells were infected with DiD-HCV (red) for...
(A and B) Huh-7.5 spheroids were serum starved, incubated with 5 μM AG-1478 (A) or sorafenib (B) for...
(A-F) Huh-7.5 spheroids were incubated with DMSO or 5 μM AG-1478 for 2h, infected with DiD-HCV (red)...
(A) Huh-7.5 wildtype, OCLN CRISPR’ed, or complemented cells were seeded onto 96-well plates, infecte...
<p>For (A) and (B) the hepatoma cell lines Huh7 and Huh7.5 were cultured for 48 hours while primary ...
<p><b>A</b>) ARPE-19 cells were transduced with Ad-tet-trans alone (Normal) or Ad-PDGFRα and Ad-tet-...
<p>The nuclear receptor mediated pathway is activated by E2 and blocked by Tamoxifen (Tam) in most c...
(A) Western blot of Huh-7.5 wildtype, CLDN1 CRISPR’ed, and complemented cells. (B) Huh-7.5 wildtype,...
Le virus de l'hépatite C (HCV) est une cause majeure de maladie chronique du foie et de carcinome hé...
Hepatitis C virus (HCV) is a model for the study of virus–host interaction and host cell responses t...
<p>To evaluate the possible routes of HCV infection, the mRNA (A) and protein (B) expression of vari...
International audienceHepatitis C virus (HCV) is a major cause of liver disease, but therapeutic opt...