We communicate a strategy for the hydrofunctionalization of 1,3-dienes via Rh-hydride catalysis. Conjugated dienes are coupled to nucleophiles to demonstrate the feasibility of novel C-C, C-O, C-S, and C-N bond forming processes. In the presence of a chiral JoSPOphos ligand, hydroamination generates chiral allylic amines with high regio- and enantioselectivity. Tuning both the pKa and steric properties of an acid-additive is critical for enantiocontrol
A rhodium(I) catalyst incorporating the Me-DuPhos ligand promotes enantioselective intermolecular hy...
Rh-catalyzed enantioselective hydrogenation of oxime acetates was first reported, which afforded a n...
A Rh-catalyzed enantioselective hydroamination of allylamines using a chiral BIPHEP-type ligand is r...
A comprehensive mechanistic study on the title reaction by using DFT(B3LYP-D3) computational method ...
Hydrofunctionalization, which is defined as the addition of a hydrogen atom and another fragment to ...
We report an enantioselective coupling between alkynes and indoles. A Rh-hydride catalyst isomerizes...
Under Rh(I) catalysis, α-ketoamides undergo intermolecular hydroacylation with aliphatic aldehydes. ...
Under Rh(I) catalysis, α-ketoamides undergo intermolecular hydroacylation with aliphatic aldehyd...
Hydrofunctionalizations are an attractive method for functionalizing olefins, forging new bonds in a...
A comprehensive mechanistic study on the title reaction by using DFT(B3LYP-D3) computational method...
We report the development of highly enantio- and regioselective Pd-catalyzed intermolecular hydroami...
The hydroamination of internal alkynes via tandem rhodium catalysis gives branched <i>N</i>-allylic ...
We report a Rh-catalyzed hydrothiolation of 1,3-dienes, including petroleum feedstocks. Either secon...
We report an enantioselective coupling between alkynes and indoles. A Rh-hydride catalyst isomerize...
We report a Rh-catalyzed hydrothiolation of 1,3-dienes, including petroleum feedstocks. Either secon...
A rhodium(I) catalyst incorporating the Me-DuPhos ligand promotes enantioselective intermolecular hy...
Rh-catalyzed enantioselective hydrogenation of oxime acetates was first reported, which afforded a n...
A Rh-catalyzed enantioselective hydroamination of allylamines using a chiral BIPHEP-type ligand is r...
A comprehensive mechanistic study on the title reaction by using DFT(B3LYP-D3) computational method ...
Hydrofunctionalization, which is defined as the addition of a hydrogen atom and another fragment to ...
We report an enantioselective coupling between alkynes and indoles. A Rh-hydride catalyst isomerizes...
Under Rh(I) catalysis, α-ketoamides undergo intermolecular hydroacylation with aliphatic aldehydes. ...
Under Rh(I) catalysis, α-ketoamides undergo intermolecular hydroacylation with aliphatic aldehyd...
Hydrofunctionalizations are an attractive method for functionalizing olefins, forging new bonds in a...
A comprehensive mechanistic study on the title reaction by using DFT(B3LYP-D3) computational method...
We report the development of highly enantio- and regioselective Pd-catalyzed intermolecular hydroami...
The hydroamination of internal alkynes via tandem rhodium catalysis gives branched <i>N</i>-allylic ...
We report a Rh-catalyzed hydrothiolation of 1,3-dienes, including petroleum feedstocks. Either secon...
We report an enantioselective coupling between alkynes and indoles. A Rh-hydride catalyst isomerize...
We report a Rh-catalyzed hydrothiolation of 1,3-dienes, including petroleum feedstocks. Either secon...
A rhodium(I) catalyst incorporating the Me-DuPhos ligand promotes enantioselective intermolecular hy...
Rh-catalyzed enantioselective hydrogenation of oxime acetates was first reported, which afforded a n...
A Rh-catalyzed enantioselective hydroamination of allylamines using a chiral BIPHEP-type ligand is r...