International audienceOBJECTIVES: This study examines the role of insulin and angiotensin II in high-density lipoprotein (HDL) metabolism by focusing on the regulation and function of scavenger receptor type-BI (SR-BI) in adipose tissue. METHODS AND RESULTS: Insulin or angiotensin II injection in wild-type mice induced a decrease in circulating HDL and it was associated with the translocation of SR-BI from intracellular sites to the plasma membrane of adipose tissue. Refeeding upregulated adipose HDL selective cholesteryl esters uptake and SR-BI proteins through transcriptional and posttranscriptional mechanisms. This occurred along with a decrease in serum HDL and an increase in adipose cholesterol content. Similar results were obtained wi...
Objective—Scavenger receptors play crucial roles in the pathogenesis of atherosclerosis, but their r...
Adipose tissue contains one of the largest reservoirs of cholesterol in the body. Adipocyte dysfunct...
High density lipoprotein (HDL) was reported to decrease plasma glucose and promote insulin secretion...
Brown adipocytes within brown adipose tissue (BAT) and beige adipocytes within white adipose tissue ...
Obesity is associated with a number of complications that may increase the risk for chronic disease,...
Endothelial lipase (EL) is a negative regulator of high density lipoprotein (HDL) cholesterol plasma...
This study aims to determine whether dysfunctional High Density Lipoprotein (HDL) influenced the exp...
Scavenger receptor BI (SR-BI) is a selective uptake receptor for HDL cholesterol but is also involve...
Scavenger receptor class B, type I (SRBI) is a key regulator of high density lipoprotein (HDL) metab...
<b>Objective</b> The objective of the current study was to investigate the hypothesis t...
BACKGROUND: High density lipoprotein (HDL) was reported to decrease plasma glucose and promote insul...
Objective:We tested the hypothesis that enlarged, dysfunctional HDL (high-density lipoprotein) parti...
Brown and beige adipocytes combust nutrients for thermogenesis and through their metabolic activity ...
Objective-Recently, we demonstrated that scavenger receptor type BI (SR-BI), a high-density lipoprot...
Background: Scavenger receptor BI (SR-BI) is a classic high-density lipoprotein (HDL) receptor, whic...
Objective—Scavenger receptors play crucial roles in the pathogenesis of atherosclerosis, but their r...
Adipose tissue contains one of the largest reservoirs of cholesterol in the body. Adipocyte dysfunct...
High density lipoprotein (HDL) was reported to decrease plasma glucose and promote insulin secretion...
Brown adipocytes within brown adipose tissue (BAT) and beige adipocytes within white adipose tissue ...
Obesity is associated with a number of complications that may increase the risk for chronic disease,...
Endothelial lipase (EL) is a negative regulator of high density lipoprotein (HDL) cholesterol plasma...
This study aims to determine whether dysfunctional High Density Lipoprotein (HDL) influenced the exp...
Scavenger receptor BI (SR-BI) is a selective uptake receptor for HDL cholesterol but is also involve...
Scavenger receptor class B, type I (SRBI) is a key regulator of high density lipoprotein (HDL) metab...
<b>Objective</b> The objective of the current study was to investigate the hypothesis t...
BACKGROUND: High density lipoprotein (HDL) was reported to decrease plasma glucose and promote insul...
Objective:We tested the hypothesis that enlarged, dysfunctional HDL (high-density lipoprotein) parti...
Brown and beige adipocytes combust nutrients for thermogenesis and through their metabolic activity ...
Objective-Recently, we demonstrated that scavenger receptor type BI (SR-BI), a high-density lipoprot...
Background: Scavenger receptor BI (SR-BI) is a classic high-density lipoprotein (HDL) receptor, whic...
Objective—Scavenger receptors play crucial roles in the pathogenesis of atherosclerosis, but their r...
Adipose tissue contains one of the largest reservoirs of cholesterol in the body. Adipocyte dysfunct...
High density lipoprotein (HDL) was reported to decrease plasma glucose and promote insulin secretion...