Homeodomain proteins contain a 60 amino acid DNA binding motif called homeobox that regulates a variety of developmental events. Recently, a novel cluster of homeobox genes has been discovered on the X chromosome of the mouse. Because of their selective expression in reproductive organs, they are named Reproductive homeobox genes on the X chromosome (Rhox). Rhox6, a member of the Rhox family, is expressed in primordial germ cells (PGCs) in the developing gonad and the placenta, although the biological function of Rhox6 in determination of PGCs and placental cells remains unknown. To investigate the Rhox6 function, we generated male chimeras by injection of the gene-trapped embryonic stem cells (ESCs) harboring a hypomorphic mutation in Rho...
The Reproductive Homeobox X-linked, Rhox, genes encode transcription factors that are expressed excl...
RNA interference (RNAi) is widely used to determine the function of genes. We chose this approach to...
In Drosophila, XX embryos express Sxl from the early promoter, SxlPe, and become females. At the sam...
Homeodomain proteins contain a 60 amino acid DNA binding motif called homeobox that regulates a vari...
Homeodomain proteins contain a 60 amino acid DNA binding motif called homeobox that regulates a vari...
International audienceThe reproductive homeobox on the X chromosome (RHOX) genes were first identifi...
Homeobox genes play essential roles in embryonic development and reproduction. Recently, a large clu...
The Reproductive Homeobox X-linked, Rhox, genes encode transcription factors that are expressed excl...
Homeobox proteins are transcription factors that play key roles in the process of embryogenesis. Her...
Germ cell development is a highly coordinated process driven, in part, by regulatory mechanisms that...
SummaryHomeobox genes encode transcription factors notable for their ability to regulate embryogenes...
The X-linked mouse Rhox gene cluster contains over 30 homeobox genes that are candidates to regulate...
Abstract Background Mouse embryonic stem cells (mESCs) not only retain the property of self-renewal ...
Mammalian ovulation is a complex, hormone-dependent developmental program in which several events mu...
Epithelial morphogenesis is contingent upon cell shape changes. Cell shape changes are the driving f...
The Reproductive Homeobox X-linked, Rhox, genes encode transcription factors that are expressed excl...
RNA interference (RNAi) is widely used to determine the function of genes. We chose this approach to...
In Drosophila, XX embryos express Sxl from the early promoter, SxlPe, and become females. At the sam...
Homeodomain proteins contain a 60 amino acid DNA binding motif called homeobox that regulates a vari...
Homeodomain proteins contain a 60 amino acid DNA binding motif called homeobox that regulates a vari...
International audienceThe reproductive homeobox on the X chromosome (RHOX) genes were first identifi...
Homeobox genes play essential roles in embryonic development and reproduction. Recently, a large clu...
The Reproductive Homeobox X-linked, Rhox, genes encode transcription factors that are expressed excl...
Homeobox proteins are transcription factors that play key roles in the process of embryogenesis. Her...
Germ cell development is a highly coordinated process driven, in part, by regulatory mechanisms that...
SummaryHomeobox genes encode transcription factors notable for their ability to regulate embryogenes...
The X-linked mouse Rhox gene cluster contains over 30 homeobox genes that are candidates to regulate...
Abstract Background Mouse embryonic stem cells (mESCs) not only retain the property of self-renewal ...
Mammalian ovulation is a complex, hormone-dependent developmental program in which several events mu...
Epithelial morphogenesis is contingent upon cell shape changes. Cell shape changes are the driving f...
The Reproductive Homeobox X-linked, Rhox, genes encode transcription factors that are expressed excl...
RNA interference (RNAi) is widely used to determine the function of genes. We chose this approach to...
In Drosophila, XX embryos express Sxl from the early promoter, SxlPe, and become females. At the sam...