Background: The purpose of the research is to identify the main active ingredients in Coptidis Rhizoma (CR) and explore the possible molecular mechanisms in the treatment of Kawasaki disease (KD).Materials and Methods: A total of 58 children with KD were randomly divided into a control group and a Berberine treatment group. The therapeutic indicators of the two groups before and after treatment were compared. Then, compounds and drug targets of CR from the TCMSP, SWISS, SEA, and the STITCH were collected, and targeted KD genes were retrieved from the DisGeNET, DrugBank, and GeneCards databases. The network pharmacology approach involved network construction, target prediction, and module analysis. GO and KEGG enrichment analysis were perfor...
Kawasaki Disease (KD) is an acute inflammatory illness that mostly occurs in children below 5 years ...
Evidence of the advantages of Coptidis Rhizoma (CR) for the treatment of ulcerative colitis (UC) is ...
Purpose:Prunella vulgaris (PV), a traditional Chinese medicine, has been used to treat patients with...
BACKGROUND: Global gene expression profiling can provide insight into the underlying pathophysiology...
Kawasaki disease (KD) is a systemic vasculitis of unknown etiology and it is therefore worth examini...
Kawasaki disease (KD) is a complex disease, leading to the damage of multisystems. The pathogen that...
Copyright © 2013 Yu-wen Lv et al. This is an open access article distributed under the Creative Comm...
Kawasaki disease (KD) is an inflammatory disease in children associated with vasculitis affecting pr...
Background. Although the combination of Zingiberis rhizoma (ZR) and Coptidis rhizoma (CR) is a class...
Kawasaki disease (KD) is a systemic vasculitis of unknown etiology. Absence of definitive diagnostic...
Kawasaki disease (KD) is anacute febrile coronary vasculitis disease in children. In general, this d...
Kawasaki disease (KD) is an acute inflammatory disorder of early childhood. It causes coronary arter...
BACKGROUND: Kawasaki Disease (KD) can cause potentially life-threatening coronary arteritis in young...
Kawasaki disease (KD) has been declared a rare idiopathic condition for a long time. The children ag...
Kawasaki disease (KD) is an acute self-limiting inflammatory disorder, associated with vasculitis, a...
Kawasaki Disease (KD) is an acute inflammatory illness that mostly occurs in children below 5 years ...
Evidence of the advantages of Coptidis Rhizoma (CR) for the treatment of ulcerative colitis (UC) is ...
Purpose:Prunella vulgaris (PV), a traditional Chinese medicine, has been used to treat patients with...
BACKGROUND: Global gene expression profiling can provide insight into the underlying pathophysiology...
Kawasaki disease (KD) is a systemic vasculitis of unknown etiology and it is therefore worth examini...
Kawasaki disease (KD) is a complex disease, leading to the damage of multisystems. The pathogen that...
Copyright © 2013 Yu-wen Lv et al. This is an open access article distributed under the Creative Comm...
Kawasaki disease (KD) is an inflammatory disease in children associated with vasculitis affecting pr...
Background. Although the combination of Zingiberis rhizoma (ZR) and Coptidis rhizoma (CR) is a class...
Kawasaki disease (KD) is a systemic vasculitis of unknown etiology. Absence of definitive diagnostic...
Kawasaki disease (KD) is anacute febrile coronary vasculitis disease in children. In general, this d...
Kawasaki disease (KD) is an acute inflammatory disorder of early childhood. It causes coronary arter...
BACKGROUND: Kawasaki Disease (KD) can cause potentially life-threatening coronary arteritis in young...
Kawasaki disease (KD) has been declared a rare idiopathic condition for a long time. The children ag...
Kawasaki disease (KD) is an acute self-limiting inflammatory disorder, associated with vasculitis, a...
Kawasaki Disease (KD) is an acute inflammatory illness that mostly occurs in children below 5 years ...
Evidence of the advantages of Coptidis Rhizoma (CR) for the treatment of ulcerative colitis (UC) is ...
Purpose:Prunella vulgaris (PV), a traditional Chinese medicine, has been used to treat patients with...