Efek gel ekstrak daun kemangi (Ocimum sanctum l.) terhadap luas ulkus traumatikus pada Rattus norvegicus

  • Sa'adah, Nikmatus
  • Hendarti, Hening Tuti
  • Prehananto, Herlambang
  • Soebadi, Bagus
  • Pertiwi, Eka Putri
  • Adriansyah, Agus Aan
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Publication date
June 2021
Publisher
Poltekkes Kemenkes Semarang

Abstract

Introduction: Traumatic ulcers are damage to the mucosal tissue of the oral cavity which causes some of the epithelial structures to be lost to exceed the basement membrane or even reach the lamina propia. The causes of ulcers is trauma, which can be physical, mechanical, thermal or chemical trauma. One of traditional treatments for traumatic ulcers is basil (Ocimum sanctum L.) leaves which contain such as alkaloids, saponins, flavonoids, and tannins as anti-inflammatory. This research was aimed to prove the effect of basil leaves (Ocimum sanctum L.) extract gel with a concentration of 0.5%, 1%, and 1.5% to traumatic ulcer area in Rattus norvegicus. Method: Laboratory experimental study with a post test only control group design. The basil ...

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