Computational strategies to combat COVID-19: useful tools to accelerate SARS-CoV-2 and coronavirus research.
- Hufsky, Franziska
- Lamkiewicz, Kevin
- Almeida, Alexandre
- Aouacheria, Abdel
- Arighi, Cecilia
- Bateman, Alex
- Baumbach, Jan
- Beerenwinkel, Niko
- Brandt, Christian
- Cacciabue, Marco
- Chuguransky, Sara
- Drechsel, Oliver
- Finn, Robert D
- Fritz, Adrian
- Fuchs, Stephan
- Hattab, Georges
- Hauschild, Anne-Christin
- Heider, Dominik
- Hoffmann, Marie
- Hölzer, Martin
- Hoops, Stefan
- Kaderali, Lars
- Kalvari, Ioanna
- von Kleist, Max
- Kmiecinski, Renó
- Kühnert, Denise
- Lasso, Gorka
- Libin, Pieter
- List, Markus
- Löchel, Hannah F
- Martin, Maria J
- Martin, Roman
- Matschinske, Julian
- McHardy, Alice C
- Mendes, Pedro
- Mistry, Jaina
- Navratil, Vincent
- Nawrocki, Eric P
- O'Toole, Áine Niamh
- Ontiveros-Palacios, Nancy
- Petrov, Anton I
- Rangel-Pineros, Guillermo
- Redaschi, Nicole
- Reimering, Susanne
- Reinert, Knut
- Reyes, Alejandro
- Richardson, Lorna
- Robertson, David L
- Sadegh, Sepideh
- Singer, Joshua B
- Theys, Kristof
- Upton, Chris
- Welzel, Marius
- Williams, Lowri
- Marz, Manja
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DOIAbstract
SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) is a novel virus of the family Coronaviridae. The virus causes the infectious disease COVID-19. The biology of coronaviruses has been studied for many years. However, bioinformatics tools designed explicitly for SARS-CoV-2 have only recently been developed as a rapid reaction to the need for fast detection, understanding and treatment of COVID-19. To control the ongoing COVID-19 pandemic, it is of utmost importance to get insight into the evolution and pathogenesis of the virus. In this review, we cover bioinformatics workflows and tools for the routine detection of SARS-CoV-2 infection, the reliable analysis of sequencing data, the tracking of the COVID-19 pandemic and evaluation...