The essential Schizosaccharomyces pombe Pfh1 DNA helicase promotes fork movement past Gquadruplex motifs to prevent DNA damage. BMC biology, 12 Access to the published version may require subscription. N.B. When citing this work, cite the original published paper. Permanent link to this version: http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-96998 R E S E A R C H A R T I C L E Open Access The essential Schizosaccharomyces pombe Pfh1 DNA helicase promotes fork movement past G-quadruplex motifs to prevent DNA damage Nasim Sabouri 1*? , John A Capra 2*? and Virginia A Zakian 3 Abstract Background: G-quadruplexes (G4s) are stable non-canonical DNA secondary structures consisting of stacked arrays of four guanines, each held together by Hoogs...
The Saccharomyces cerevisiae Pif1 helicase is the prototypical member of the Pif1 DNA helicase famil...
2014-01-14A healthy cell needs to accurately duplicate its genome and pass one copy to each of its d...
Pfh1, the sole member of the Pif1 helicases in Schizosaccharomyces pombe, is multifunctional and ess...
Background: G-quadruplexes (G4s) are stable non-canonical DNA secondary structures consisting of sta...
DNA stores the genetic information of all living organisms, and this information needs to be copied ...
Eukaryotic cells have two sets of genomes, the nuclear and mitochondrial, and both need to be accura...
Certain guanine-rich sequences have an inherent propensity to form G-quadruplex (G4) structures. G4 ...
G-quadruplex (G4) structures are stable noncanonical DNA structures that are implicated in the regul...
SummaryG-quadruplex (G4) DNA structures are extremely stable four-stranded secondary structures held...
<div><p>Replicative DNA helicases expose the two strands of the double helix to the replication appa...
The Schizosaccharomyces pombe pfh1+ gene (PIF1 homolog) encodes an essential enzyme that has both DN...
In order to understand in which biological processes the four-stranded G-quadruplex (G4) DNA structu...
Our genome contains many G-rich sequences, which have the propensity to fold into stable secondary D...
Summary: DNA breaks are complex lesions that can be repaired either by non-homologous end joining (N...
The Saccharomyces cerevisiae Pif1 helicase is the prototypical member of the Pif1 DNA helicase famil...
2014-01-14A healthy cell needs to accurately duplicate its genome and pass one copy to each of its d...
Pfh1, the sole member of the Pif1 helicases in Schizosaccharomyces pombe, is multifunctional and ess...
Background: G-quadruplexes (G4s) are stable non-canonical DNA secondary structures consisting of sta...
DNA stores the genetic information of all living organisms, and this information needs to be copied ...
Eukaryotic cells have two sets of genomes, the nuclear and mitochondrial, and both need to be accura...
Certain guanine-rich sequences have an inherent propensity to form G-quadruplex (G4) structures. G4 ...
G-quadruplex (G4) structures are stable noncanonical DNA structures that are implicated in the regul...
SummaryG-quadruplex (G4) DNA structures are extremely stable four-stranded secondary structures held...
<div><p>Replicative DNA helicases expose the two strands of the double helix to the replication appa...
The Schizosaccharomyces pombe pfh1+ gene (PIF1 homolog) encodes an essential enzyme that has both DN...
In order to understand in which biological processes the four-stranded G-quadruplex (G4) DNA structu...
Our genome contains many G-rich sequences, which have the propensity to fold into stable secondary D...
Summary: DNA breaks are complex lesions that can be repaired either by non-homologous end joining (N...
The Saccharomyces cerevisiae Pif1 helicase is the prototypical member of the Pif1 DNA helicase famil...
2014-01-14A healthy cell needs to accurately duplicate its genome and pass one copy to each of its d...
Pfh1, the sole member of the Pif1 helicases in Schizosaccharomyces pombe, is multifunctional and ess...