The essential Schizosaccharomyces pombe Pfh1 DNA helicase promotes fork movement past G-quadruplex motifs to prevent DNA damage

  • N Sabouri
  • J A Capra
  • V A Zakian
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Publication date
January 2014

Abstract

The essential Schizosaccharomyces pombe Pfh1 DNA helicase promotes fork movement past Gquadruplex motifs to prevent DNA damage. BMC biology, 12 Access to the published version may require subscription. N.B. When citing this work, cite the original published paper. Permanent link to this version: http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-96998 R E S E A R C H A R T I C L E Open Access The essential Schizosaccharomyces pombe Pfh1 DNA helicase promotes fork movement past G-quadruplex motifs to prevent DNA damage Nasim Sabouri 1*? , John A Capra 2*? and Virginia A Zakian 3 Abstract Background: G-quadruplexes (G4s) are stable non-canonical DNA secondary structures consisting of stacked arrays of four guanines, each held together by Hoogs...

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