Andrographolide undergoes modification after illumination by blue laser in the presence of sodium bicarbonate
- Putra, Andrianopsyah Mas Jaya
- Kurnia, Siti Rahmah
- Marjani, Fathimah Nurmajdina
- Ernawati, Teni
- Isnaeni, Isnaeni
- Lotulung, Puspa Dewi Narrij
- Sundowo, Andini
- Simanjuntak, Ernawati
- Megawati, Megawati
- Yanuar, Arry
- Chaidir, Chaidir
- Hanafi, Muhammad
View in ORKG Publication date
November 2020
DOI Publisher
CSIR-National Institute of Science Communication and Policy Research (NIScPR)Abstract
Andrographolide is the marker compound of Andrographis paniculata (Kalmegh), a herb that constitutes many traditional Asian remedies. In the present photochemical approach to modify its 12-en-14-hydroxyl moiety into 13-enone, a methanol solution of andrographolide has been illuminated with blue laser for 6 hours in the presence of sodium bicarbonate. After the illumination, it has been discovered that the 12-en-14-hydroxyl moiety undergoes modification into the 11-enone.