A multicenter measurement of magnetization transfer ratio in normal white matter
- Berry, Isabelle
- Barker, Gareth J.
- Barkhof, Frederik
- Campi, Adriana
- Dousset, Vincent
- Franconi, Jean-Michel
- Gass, Achim
- Schreiber, Wolfgang
- Miller, David H.
- Tofts, Paul S.
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DOIAbstract
To assess the importance of intercenter variations when measuring magnetization transfer ratio (MTR) in the brain, six European centers measured MTR in normal white matter. MTR ranged from 9 to 51 percent units (25 sequences). The effective flip angle of the saturating pulse divided by the pulse repetition time (ENRsat degrees/msec) was a good predictor of MTR (MTR = 3.25 ENRsat)