Inhibitory effects of Taraxacum mongolicum with phreatic water on melanin synthesis

  • Jang, Moon-Hee
  • Ahn, Taek-Won
ORKG logo View in ORKG
Publication date
June 2015
Publisher
Published by Elsevier Korea LLC.

Abstract

AbstractBackgroundRecently, people have begun showing heightened interest in skin whitening. Melanin is an important factor that determines skin color. The purpose of this study is to investigate the inhibitory effect of Taraxacum mongolicum (TAM) with phreatic water (PW) from Dogo Hot Springs on melanin synthesis.MethodsWe assessed the inhibitory effects of TAM on melanin synthesis in B16F10 mouse melanoma cells. The mRNA levels of tyrosinase related protein (TRP)-1, TRP-2, tyrosinase, MITF, ERK, and PKA protein were analyzed with reverse transcription polymerase chain reaction and Western blot analysis. We also assessed the inhibitory effects of TAM with PW on melanin synthesis in HRM-2 melanin-possessing hairless mice. After UVB irradiat...

Extracted data

We use cookies to provide a better user experience.