Expression of the cell-surface protein CD47 allows some normal cells to avoid phagocytosis by macrophages. In this issue, Jaiswal et al. (2009) and Majeti et al. (2009) show that elevated CD47 expression by leukemic stem cells inhibits macrophage activity and is an indicator of poor prognosis for patients with acute myeloid leukemia
Myelofibrosis (MF) is characterized by increased circulating hematopoietic progenitor cells (HPCs), ...
AuthOr’S VIew AuthOr’S VIew CD47 is a valuable target for anticancer therapy due to its function as ...
Abstract CD47, or integrin-associated protein, is a cell surface ligand expressed in low levels by n...
Expression of the cell-surface protein CD47 allows some normal cells to avoid phagocytosis by macrop...
Acute myeloid leukemia (AML) is organized as a cellular hierarchy initiated and maintained by a subs...
SummaryAcute myeloid leukemia (AML) is organized as a cellular hierarchy initiated and maintained by...
Macrophages clear pathogens and damaged or aged cells from the blood stream via phagocytosis. Cell-s...
SummaryMacrophages clear pathogens and damaged or aged cells from the blood stream via phagocytosis....
CD47, expressed on a variety of tumor cells, confers immune resistance by delivering an inhibitory &...
Binding of CD47 to signal regulatory protein alpha (SIRPα), an inhibitory receptor, negatively regul...
Increased phagocytosis of AML cells by macrophages following CD47 Knockdown. MEGAN SHARP Msc Biomedi...
CD47 is a transmembrane glycoprotein with a high expression in both, healthy and cancer (stem) cells...
Accumulating evidence indicates that a small subset of cancer cells, termed the tumor-initiating cel...
the editor: Is targeting of CD47-SIRP enough for treating hematopoietic malignancy? With interest w...
CD47 is a widely expressed cell surface protein that functions as a regulator of phagocyto-sis media...
Myelofibrosis (MF) is characterized by increased circulating hematopoietic progenitor cells (HPCs), ...
AuthOr’S VIew AuthOr’S VIew CD47 is a valuable target for anticancer therapy due to its function as ...
Abstract CD47, or integrin-associated protein, is a cell surface ligand expressed in low levels by n...
Expression of the cell-surface protein CD47 allows some normal cells to avoid phagocytosis by macrop...
Acute myeloid leukemia (AML) is organized as a cellular hierarchy initiated and maintained by a subs...
SummaryAcute myeloid leukemia (AML) is organized as a cellular hierarchy initiated and maintained by...
Macrophages clear pathogens and damaged or aged cells from the blood stream via phagocytosis. Cell-s...
SummaryMacrophages clear pathogens and damaged or aged cells from the blood stream via phagocytosis....
CD47, expressed on a variety of tumor cells, confers immune resistance by delivering an inhibitory &...
Binding of CD47 to signal regulatory protein alpha (SIRPα), an inhibitory receptor, negatively regul...
Increased phagocytosis of AML cells by macrophages following CD47 Knockdown. MEGAN SHARP Msc Biomedi...
CD47 is a transmembrane glycoprotein with a high expression in both, healthy and cancer (stem) cells...
Accumulating evidence indicates that a small subset of cancer cells, termed the tumor-initiating cel...
the editor: Is targeting of CD47-SIRP enough for treating hematopoietic malignancy? With interest w...
CD47 is a widely expressed cell surface protein that functions as a regulator of phagocyto-sis media...
Myelofibrosis (MF) is characterized by increased circulating hematopoietic progenitor cells (HPCs), ...
AuthOr’S VIew AuthOr’S VIew CD47 is a valuable target for anticancer therapy due to its function as ...
Abstract CD47, or integrin-associated protein, is a cell surface ligand expressed in low levels by n...
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