In vitro metabolite assessment of 68Ga-labelled trimers by artificial enzymatic degradation.

Use of In Vitro Systems To Model In Vivo Degradation of Therapeutic Monoclonal Antibodies

Na Yang (266025)
Qing Tang (167623)
Ping Hu (59156)
Michael J. Lewis (373664)

June 2018

Major degradation pathways such as deamidation, isomerization, oxidation, and glycation may be accel...

Amounts of metabolites in glycolysis, the OPP pathway and the Calvin cycle

Hideyuki Takahashi (11701)
Hirofumi Uchimiya (52950)
Yukako Hihara (52951)

December 2011

Wild-type and Δ mutant were grown photoautotrophically (white bars) or photomixotrophically (black b...

Assessment of automated trimethylsilyl derivatization protocols for GC–MS-based untargeted metabolomic analysis of urine

Abbiss, H.
Rawlinson, C.
Maker, G.L.
Trengove, R.

January 2015

Gas chromatography–mass spectrometry (GC–MS) is a commonly used metabolomic platform for the analysi...

In vitro stability assessment of 68Ga-labelled trimers in fresh human serum.

Dominik Summer (1359228)
Andrea Kroess (5571089)
Rudolf Woerndle (5571092)
Christine Rangger (1359234)
Maximilian Klingler (4015679)
Hubertus Haas (194198)
Leopold Kremser (122455)
Herbert H. Lindner (1357815)
Elisabeth von Guggenberg (3761320)
Clemens Decristoforo (687544)

July 2018

Radio-RP-HPLC analysis of the supernatant of 68Ga-labelled trimeric Met- (A) and Nle (...

In vitro metabolite assessment of non-radioactive trimers by artificial enzymatic degradation.

Dominik Summer (1359228)
Andrea Kroess (5571089)
Rudolf Woerndle (5571092)
Christine Rangger (1359234)
Maximilian Klingler (4015679)
Hubertus Haas (194198)
Leopold Kremser (122455)
Herbert H. Lindner (1357815)
Elisabeth von Guggenberg (3761320)
Clemens Decristoforo (687544)

July 2018

Representative RP-HPLC chromatograms of artificial enzymatic degradation in vitro of metal...

In vitro metabolite assessment, purification and identification of non-radioactive metabolites formed by artificial enzymatic degradation.

Dominik Summer (1359228)
Andrea Kroess (5571089)
Rudolf Woerndle (5571092)
Christine Rangger (1359234)
Maximilian Klingler (4015679)
Hubertus Haas (194198)
Leopold Kremser (122455)
Herbert H. Lindner (1357815)
Elisabeth von Guggenberg (3761320)
Clemens Decristoforo (687544)

July 2018

Representative RP-HPLC chromatograms (UV absorption at λ = 220 nm) of enzymatic degradation of Fe...

In vivo stability of 68Ga-labelled mono- and multimeric Nle-MG based conjugates.

Dominik Summer (1359228)
Andrea Kroess (5571089)
Rudolf Woerndle (5571092)
Christine Rangger (1359234)
Maximilian Klingler (4015679)
Hubertus Haas (194198)
Leopold Kremser (122455)
Herbert H. Lindner (1357815)
Elisabeth von Guggenberg (3761320)
Clemens Decristoforo (687544)

July 2018

Representative radio-RP-HPLC chromatograms of supernatants analysed from in vivo samples, ...

Biotransformation of genistein in the rat: elucidation of metabolite structure by product ion mass fragmentology.

COLDHAM N. G
HOWELLS L
SANTI A
LANGLAIS C
KING L
MACPHERSON D. D
SAUER M. J.
MONTESISSA, CLARA

January 1999

Biotransformation of the phytoestrogen [C-14]genistein was investigated in male and female rats by a...

Degradation Study of Peptide-Drug Conjugates Using LC-MS

Dessidianti Rachma

December 2020

I aimed to study the degradation of peptide drug conjugates. The conjugates contained daunomycin (dr...

Metabolite measurements

Roessner, U
Beckles, DM

January 2009

Metabolites are the products of enzyme-catalyzed reactions that occur naturally within living cells....

Representative metabolite analysis of 67Ga-labeled 5a at 60 min post injection into a Sprague-Dawley rat (a time point compatible with 68Ga imaging).

Vijay Sharma (651200)
Jothilingam Sivapackiam (651201)
Scott E. Harpstrite (651202)
Julie L. Prior (651203)
Hannah Gu (651204)
Nigam P. Rath (651205)
David Piwnica-Worms (178244)

October 2014

Peaks are offset for clarity. Note the presence of a parental compound in all tissues.</p

Metabolic enzymes modified by phosphorylation and metabolites quantification in trypomastigotes incubated with ECM.

Eliciane C. Mattos (129459)
Gisele Canuto (6307709)
Nubia C. Manchola (6377702)
Rubens D. M. Magalhães (395962)
Thomas W. M. Crozier (577010)
Douglas J. Lamont (138243)
Marina F. M. Tavares (768493)
Walter Colli (129461)
Michael A. J. Ferguson (166662)
Maria Júlia M. Alves (5653426)

February 2019

(A) Schematic representation of enzymes from the glycolytic and glycolytic branch modified by phosph...

Metabolic fate of endogenous molecular damage: Urinary glutathione conjugates of DNA-derived base propenals as markers of inflammation

Jumpathong, Watthanachai
Chan, Wan
Taghizadeh, Koli
Dedon, Peter C.
Indrakanti, Ramesh Babu

February 2015

Although mechanistically linked to disease, cellular molecules damaged by endogenous processes have ...

Development and optimization of a metabolomic method for analysis of adherent cell cultures

Danielsson, Anders
Moritz, Thomas
Mulder, Hindrik
Spégel, Peter

January 2010

In this investigation, a gas chromatography/mass spectrometry (GC/MS)-based metabolomic protocol for...

Development of metabolomic technologies for identification and quantification of intracellular metabolites.

Edwards, James L.

January 2006

Technologies developed for the detection, identification and quantification of endogenous metabolite...

Use of In Vitro Systems To Model In Vivo Degradation of Therapeutic Monoclonal Antibodies

Na Yang (266025)
Qing Tang (167623)
Ping Hu (59156)
Michael J. Lewis (373664)

June 2018

Major degradation pathways such as deamidation, isomerization, oxidation, and glycation may be accel...

Amounts of metabolites in glycolysis, the OPP pathway and the Calvin cycle

Hideyuki Takahashi (11701)
Hirofumi Uchimiya (52950)
Yukako Hihara (52951)

December 2011

Wild-type and Δ mutant were grown photoautotrophically (white bars) or photomixotrophically (black b...

Assessment of automated trimethylsilyl derivatization protocols for GC–MS-based untargeted metabolomic analysis of urine

Abbiss, H.
Rawlinson, C.
Maker, G.L.
Trengove, R.

January 2015

Gas chromatography–mass spectrometry (GC–MS) is a commonly used metabolomic platform for the analysi...

In vitro stability assessment of 68Ga-labelled trimers in fresh human serum.

Dominik Summer (1359228)
Andrea Kroess (5571089)
Rudolf Woerndle (5571092)
Christine Rangger (1359234)
Maximilian Klingler (4015679)
Hubertus Haas (194198)
Leopold Kremser (122455)
Herbert H. Lindner (1357815)
Elisabeth von Guggenberg (3761320)
Clemens Decristoforo (687544)

July 2018

Radio-RP-HPLC analysis of the supernatant of 68Ga-labelled trimeric Met- (A) and Nle (...

In vitro metabolite assessment of non-radioactive trimers by artificial enzymatic degradation.

Dominik Summer (1359228)
Andrea Kroess (5571089)
Rudolf Woerndle (5571092)
Christine Rangger (1359234)
Maximilian Klingler (4015679)
Hubertus Haas (194198)
Leopold Kremser (122455)
Herbert H. Lindner (1357815)
Elisabeth von Guggenberg (3761320)
Clemens Decristoforo (687544)

July 2018

Representative RP-HPLC chromatograms of artificial enzymatic degradation in vitro of metal...

In vitro metabolite assessment, purification and identification of non-radioactive metabolites formed by artificial enzymatic degradation.

Dominik Summer (1359228)
Andrea Kroess (5571089)
Rudolf Woerndle (5571092)
Christine Rangger (1359234)
Maximilian Klingler (4015679)
Hubertus Haas (194198)
Leopold Kremser (122455)
Herbert H. Lindner (1357815)
Elisabeth von Guggenberg (3761320)
Clemens Decristoforo (687544)

July 2018

Representative RP-HPLC chromatograms (UV absorption at λ = 220 nm) of enzymatic degradation of Fe...

In vivo stability of 68Ga-labelled mono- and multimeric Nle-MG based conjugates.

Dominik Summer (1359228)
Andrea Kroess (5571089)
Rudolf Woerndle (5571092)
Christine Rangger (1359234)
Maximilian Klingler (4015679)
Hubertus Haas (194198)
Leopold Kremser (122455)
Herbert H. Lindner (1357815)
Elisabeth von Guggenberg (3761320)
Clemens Decristoforo (687544)

July 2018

Representative radio-RP-HPLC chromatograms of supernatants analysed from in vivo samples, ...

Biotransformation of genistein in the rat: elucidation of metabolite structure by product ion mass fragmentology.

COLDHAM N. G
HOWELLS L
SANTI A
LANGLAIS C
KING L
MACPHERSON D. D
SAUER M. J.
MONTESISSA, CLARA

January 1999

Biotransformation of the phytoestrogen [C-14]genistein was investigated in male and female rats by a...

Degradation Study of Peptide-Drug Conjugates Using LC-MS

Dessidianti Rachma

December 2020

I aimed to study the degradation of peptide drug conjugates. The conjugates contained daunomycin (dr...

Metabolite measurements

Roessner, U
Beckles, DM

January 2009

Metabolites are the products of enzyme-catalyzed reactions that occur naturally within living cells....

Representative metabolite analysis of 67Ga-labeled 5a at 60 min post injection into a Sprague-Dawley rat (a time point compatible with 68Ga imaging).

Vijay Sharma (651200)
Jothilingam Sivapackiam (651201)
Scott E. Harpstrite (651202)
Julie L. Prior (651203)
Hannah Gu (651204)
Nigam P. Rath (651205)
David Piwnica-Worms (178244)

October 2014

Peaks are offset for clarity. Note the presence of a parental compound in all tissues.</p

Metabolic enzymes modified by phosphorylation and metabolites quantification in trypomastigotes incubated with ECM.

Eliciane C. Mattos (129459)
Gisele Canuto (6307709)
Nubia C. Manchola (6377702)
Rubens D. M. Magalhães (395962)
Thomas W. M. Crozier (577010)
Douglas J. Lamont (138243)
Marina F. M. Tavares (768493)
Walter Colli (129461)
Michael A. J. Ferguson (166662)
Maria Júlia M. Alves (5653426)

February 2019

(A) Schematic representation of enzymes from the glycolytic and glycolytic branch modified by phosph...

Metabolic fate of endogenous molecular damage: Urinary glutathione conjugates of DNA-derived base propenals as markers of inflammation

Jumpathong, Watthanachai
Chan, Wan
Taghizadeh, Koli
Dedon, Peter C.
Indrakanti, Ramesh Babu

February 2015

Although mechanistically linked to disease, cellular molecules damaged by endogenous processes have ...

Development and optimization of a metabolomic method for analysis of adherent cell cultures

Danielsson, Anders
Moritz, Thomas
Mulder, Hindrik
Spégel, Peter

January 2010

In this investigation, a gas chromatography/mass spectrometry (GC/MS)-based metabolomic protocol for...

Development of metabolomic technologies for identification and quantification of intracellular metabolites.

Edwards, James L.

January 2006

Technologies developed for the detection, identification and quantification of endogenous metabolite...

Use of In Vitro Systems To Model In Vivo Degradation of Therapeutic Monoclonal Antibodies

Na Yang (266025)
Qing Tang (167623)
Ping Hu (59156)
Michael J. Lewis (373664)

June 2018

Major degradation pathways such as deamidation, isomerization, oxidation, and glycation may be accel...

Amounts of metabolites in glycolysis, the OPP pathway and the Calvin cycle

Hideyuki Takahashi (11701)
Hirofumi Uchimiya (52950)
Yukako Hihara (52951)

December 2011

Wild-type and Δ mutant were grown photoautotrophically (white bars) or photomixotrophically (black b...

Assessment of automated trimethylsilyl derivatization protocols for GC–MS-based untargeted metabolomic analysis of urine

Abbiss, H.
Rawlinson, C.
Maker, G.L.
Trengove, R.

January 2015

Gas chromatography–mass spectrometry (GC–MS) is a commonly used metabolomic platform for the analysi...

<i>In vitro</i> metabolite assessment of <sup>68</sup>Ga-labelled trimers by artificial enzymatic degradation.

Abstract

Extracted data

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