Background: Metallothionein 2A (MT2A) as a stress protein, plays a protective role in gastric mucosal barrier. Its role in the development of gastric cancer (GC) is unclear. The mechanism of MT2A will be investigated in gastric tumorigenesis. Methods: MT2A expression was detected in 973 gastric specimens. The biological function was determined through ectopic expressing MT2A in vitro and in vivo. The possible downstream effectors of MT2A were investigated in NF-kappa B signaling. The protein levels of MT2A, I kappa B-alpha and p-I kappa B-alpha (ser32/36) expression were analyzed in a subset of 258 patients by IHC staining. The prognostic effects of MT2A, status of I kappa B-alpha and TNM stage were evaluated using the Kaplan-Meier metho...
Abstract Metallothioneins (MTs) are small cysteine-rich proteins that play important roles in metal ...
[[abstract]]Introduction: Dysregulation of metal ion homeostasis is associated with urothelial carci...
Introduction: Metallothionein (MT) is a low-molecular weight metal-binding protein with functional ...
Background Dysregulated nnetallothionein 2A (MT2A) has been implicated in carcinogenesis. The purpos...
Aims: Metallothionein 2A (MT2A) and nuclear factor-kappaB (NF-B) are both involved in carcinogenesis...
Abstract Background and Objectives: As a significant number of curatively treated gastric cancer pa...
Metallothioneins (MTs) belong to a family of cysteine-rich, metal-binding intracellular proteins, wh...
Esophageal cancer has the sixth highest mortality rate worldwide. Cancer-associated fibroblasts (CAF...
AbstractThe overexpression of metallothionein-2A (MT-2A) is frequently observed in invasive human br...
Contains fulltext : 185456.pdf (publisher's version ) (Closed access)PURPOSE: Meta...
Abstract Background. Metallothioneins (MTs) are low molecular weight proteins (6-7 kDa), which have ...
International audienceOsteosarcoma is the most prevalent primary bone malignancy in children and you...
Metallothioneins (MTs) are small cysteine-rich intracellular proteins with four major isoforms ident...
Metallothionein (MT) is a small, thiol rich protein released into the extracellular environment in r...
Introduction: Metallothioneins (MTs) are a group of low-molecular weight, cysteine-rich proteins. In...
Abstract Metallothioneins (MTs) are small cysteine-rich proteins that play important roles in metal ...
[[abstract]]Introduction: Dysregulation of metal ion homeostasis is associated with urothelial carci...
Introduction: Metallothionein (MT) is a low-molecular weight metal-binding protein with functional ...
Background Dysregulated nnetallothionein 2A (MT2A) has been implicated in carcinogenesis. The purpos...
Aims: Metallothionein 2A (MT2A) and nuclear factor-kappaB (NF-B) are both involved in carcinogenesis...
Abstract Background and Objectives: As a significant number of curatively treated gastric cancer pa...
Metallothioneins (MTs) belong to a family of cysteine-rich, metal-binding intracellular proteins, wh...
Esophageal cancer has the sixth highest mortality rate worldwide. Cancer-associated fibroblasts (CAF...
AbstractThe overexpression of metallothionein-2A (MT-2A) is frequently observed in invasive human br...
Contains fulltext : 185456.pdf (publisher's version ) (Closed access)PURPOSE: Meta...
Abstract Background. Metallothioneins (MTs) are low molecular weight proteins (6-7 kDa), which have ...
International audienceOsteosarcoma is the most prevalent primary bone malignancy in children and you...
Metallothioneins (MTs) are small cysteine-rich intracellular proteins with four major isoforms ident...
Metallothionein (MT) is a small, thiol rich protein released into the extracellular environment in r...
Introduction: Metallothioneins (MTs) are a group of low-molecular weight, cysteine-rich proteins. In...
Abstract Metallothioneins (MTs) are small cysteine-rich proteins that play important roles in metal ...
[[abstract]]Introduction: Dysregulation of metal ion homeostasis is associated with urothelial carci...
Introduction: Metallothionein (MT) is a low-molecular weight metal-binding protein with functional ...