The role of interleukin-2 in iron powder-induced intraocular inflammation

  • Li Xue-min
  • Wang Wei
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Publication date
January 2005
Publisher
zhonghua yan ke za zhi chinese journal of ophthalmology
Journal
0412-4081

Abstract

To investigate the role of interleukin 2 (IL-2) in iron powder-induced intraocular inflammation in rabbits.Twelve New Zealand rabbits were randomly divided into 3 groups: paracentesis of the anterior chamber was performed in the control group, and either iron powder or iron powder with soluble interleukin-2 receptor (SIL-2R) were separately injected into the anterior chamber in the other two groups. The inflammatory reaction of the anterior chamber was observed and the levels of IL-2 in aqueous humor were measured by ELISA at 3, 5, 7, and 10 days after the injections. Pathological sections with HE staining and iron staining from different eyes enucleated 10 days after the iron powder injections were compared.The inflammatory reaction of the...

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