Sham operated animals (n = 5) at 8 d after injury. Expression levels were normalized relative to the corresponding α-tubulin band. At this time point the L5 transection induced an upregulation of both proteins in all SC segments. The expression level of CATX was substantially higher than that of CATS. Data are means ± SD. CATX activities in the lumbar SC 8 d after transection in L5T, sham (n = 7, for each group) and naive animals (n = 4). Each symbol represents the value of a single animal, the bar indicates the mean for the group. CATX activity was significantly higher in L5T than in sham or naive SC. *** p ≤ 0.001. L, lumbar; C, cervical; T, thoracic.<p><b>Copyright information:</b></p><p>Taken from "Differential expression of Cathepsin S...
Cathepsin S (CatS) is a cysteine protease normally present in lysosomes. It has long been regarded a...
BACKGROUND: Spinal cord injury is a major cause of disability that has no clinically accepted treatm...
<p>(A) In sham-operated animals, cortical cells displayed diffuse and weak staining for LC3 in the c...
Fferent expression patterns in the transverse plane are symbolized by different fillings of the bars...
Fferent expression patterns in the transverse plane are symbolized by different fillings of the bars...
Er GFAP (A'-A"') and colocalization of CATX with the microglial marker PT66 (B'-B"') and the macroph...
Le spinal cord sections (A, B), in the dorsal horn (DH) (C-F), the layer IX of the ventral horn (VH)...
Le spinal cord sections (A, B), in the dorsal horn (DH) (C-F), the layer IX of the ventral horn (VH)...
L5 segment. CATS-immunopositive deposits are localized in small glial-like cells (C, E, F) that dist...
L5 segment. CATS-immunopositive deposits are localized in small glial-like cells (C, E, F) that dist...
density of PT66-immunopositive microglial cells (C-E) and GFAP-immunopositive astrocytes (F-H) is al...
Using a gene expression analysis approach we found that the mRNA encoding the lysosomal cysteine pro...
BACKGROUND: Proteases have been shown to modulate pain signaling in the spinal cord and may contribu...
The aim of our study was to investigate how the distribution and amount of cathepsin B change during...
which permits unrestricted use, distribution, and reproduction in any medium, provided the original ...
Cathepsin S (CatS) is a cysteine protease normally present in lysosomes. It has long been regarded a...
BACKGROUND: Spinal cord injury is a major cause of disability that has no clinically accepted treatm...
<p>(A) In sham-operated animals, cortical cells displayed diffuse and weak staining for LC3 in the c...
Fferent expression patterns in the transverse plane are symbolized by different fillings of the bars...
Fferent expression patterns in the transverse plane are symbolized by different fillings of the bars...
Er GFAP (A'-A"') and colocalization of CATX with the microglial marker PT66 (B'-B"') and the macroph...
Le spinal cord sections (A, B), in the dorsal horn (DH) (C-F), the layer IX of the ventral horn (VH)...
Le spinal cord sections (A, B), in the dorsal horn (DH) (C-F), the layer IX of the ventral horn (VH)...
L5 segment. CATS-immunopositive deposits are localized in small glial-like cells (C, E, F) that dist...
L5 segment. CATS-immunopositive deposits are localized in small glial-like cells (C, E, F) that dist...
density of PT66-immunopositive microglial cells (C-E) and GFAP-immunopositive astrocytes (F-H) is al...
Using a gene expression analysis approach we found that the mRNA encoding the lysosomal cysteine pro...
BACKGROUND: Proteases have been shown to modulate pain signaling in the spinal cord and may contribu...
The aim of our study was to investigate how the distribution and amount of cathepsin B change during...
which permits unrestricted use, distribution, and reproduction in any medium, provided the original ...
Cathepsin S (CatS) is a cysteine protease normally present in lysosomes. It has long been regarded a...
BACKGROUND: Spinal cord injury is a major cause of disability that has no clinically accepted treatm...
<p>(A) In sham-operated animals, cortical cells displayed diffuse and weak staining for LC3 in the c...