Ultrastructural damage is strongly reduced in <i>persephone</i> homozygotes versus wild-type siblings after neomycin exposure.

<p>n = number of fish in each category.</p><p>Damage scale:</p><p>A = All hair cells of the neuromast appear normal.</p><p>B = Slight mitochondrial swelling (modest within range of mock-treated controls).</p><p>C = One or more hair cells exhibit some mitochondrial swelling. One or more hair cells also exhibit some nuclear condensation.</p><p>D = Many hair cells show severe damage, including distended mitochondria, highly pycnotic nuclei, or condensation of the entire cell.</p><p>E = Hair cells are absent, or all hair cells show severe damage, including severely distended mitochondria, highly pycnotic nuclei, or condensation of the entire cell.