TNF-α increases the expression of IL-6 and LIF in human NPCs.

  • Xiqian Lan (219539)
  • Qiang Chen (114038)
  • Yongxiang Wang (295061)
  • Beibei Jia (219534)
  • Lijun Sun (219532)
  • Jialin Zheng (174209)
  • Hui Peng (116756)
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Publication date
February 2013

Abstract

<p><b>A–B</b>. NPCs were treated with 20 ng/mL TNF-α for 4, 8, 24 and 72 h. mRNA expression of IL-6 (A) and LIF (B) were detected by TaqMan Real Time RT-PCR. Data were normalized to GAPDH and presented as fold change compared to control. ** p<0.01 in comparison to control. Results are representative of three independent donors. <b>C–D</b>. NPCs were treated with 20 ng/mL TNF-α for 30 min, 6 h and 24 h. The supernatants were assayed for IL-6 and LIF production by ELISA. Data represent the mean ± SD of triplicate samples from a representative result of three donors. * p<0.05 in comparison to control.</p

Extracted data

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