<p>(A) BALB/c mice were immunized twice with 20 µg of recombinant Gcf or mutant GcfΔCys4 via intranasal route and specific serum antibody titers were measured by ELISA two weeks after immunization. The results represent Log<sub>2</sub> endpoint values from at least five individual mice. (B) Each group of i.n. immunized mice was challenged with 2×10<sup>6</sup> PFU RSV A2 at 4 weeks after boost immunization and the levels of RSV replication in the lungs were determined by plaque assay at day 5 post challenge. <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0032226#s2" target="_blank">Results</a> are expressed as the mean ± SEM (<i>n</i> = 6). The limit of detection was 200 PFU/gram of lungs.</p
<p>Mice was immunized twice with Gcfs sublingually or FI-RSV through foot-pad route and then challen...
<p>Mice were (mock-)vaccinated three times either intranasally with BLP-F (○) or PBS (▪) or intramus...
<p>At 90 days post-immunization, mice were challenged with 10<sup>4</sup> PFUs of FMDV C-S8c1 (proce...
<p>Each group of immune mice was challenged with 1×10<sup>6</sup> PFU RSV A2 at 4 weeks after immuni...
<p>(A) BALB/c mice were immunized twice on day 0 and day 14 with 20 µg of recombinant Gcf via indica...
(A) Schematic representation of mouse immunization and challenge schedule. BALB/c mice (N = 8 per gr...
<p>(A) G-CSF measured in the sera of mice 3 days after infection with SeV or with influenza virus ×3...
(A) Schematic representation of mouse immunization and challenge schedule. BALB/c mice (N = 6 per gr...
<p>(A) Mice were immunized twice with Gcf s.l., once with FI-RSV by food-pad injection, or 1×10<sup>...
<p>(A) SeV specific antibodies in lung homogenate of G-CSF<sup>+/+</sup> and G-CSF<sup>−/−</sup> mic...
Respiratory syncytial virus (RSV) is a common cause of lower respiratory tract illness in infants, y...
<p>Mice were immunized twice with 20 µg of wtAGcf, AGcf/BCD4, BGcf/ACD4, or wtBGcf in the presence o...
Respiratory syncytial virus (RSV) is a major cause of respiratory tract infection in infants and you...
(A) NRM elicits prefusion RSVF cross-reactive serum levels, the quantity of which is two orders of m...
RSV F and G protein specific IgG antibodies were determined by ELISA in sera collected at 3 weeks af...
<p>Mice was immunized twice with Gcfs sublingually or FI-RSV through foot-pad route and then challen...
<p>Mice were (mock-)vaccinated three times either intranasally with BLP-F (○) or PBS (▪) or intramus...
<p>At 90 days post-immunization, mice were challenged with 10<sup>4</sup> PFUs of FMDV C-S8c1 (proce...
<p>Each group of immune mice was challenged with 1×10<sup>6</sup> PFU RSV A2 at 4 weeks after immuni...
<p>(A) BALB/c mice were immunized twice on day 0 and day 14 with 20 µg of recombinant Gcf via indica...
(A) Schematic representation of mouse immunization and challenge schedule. BALB/c mice (N = 8 per gr...
<p>(A) G-CSF measured in the sera of mice 3 days after infection with SeV or with influenza virus ×3...
(A) Schematic representation of mouse immunization and challenge schedule. BALB/c mice (N = 6 per gr...
<p>(A) Mice were immunized twice with Gcf s.l., once with FI-RSV by food-pad injection, or 1×10<sup>...
<p>(A) SeV specific antibodies in lung homogenate of G-CSF<sup>+/+</sup> and G-CSF<sup>−/−</sup> mic...
Respiratory syncytial virus (RSV) is a common cause of lower respiratory tract illness in infants, y...
<p>Mice were immunized twice with 20 µg of wtAGcf, AGcf/BCD4, BGcf/ACD4, or wtBGcf in the presence o...
Respiratory syncytial virus (RSV) is a major cause of respiratory tract infection in infants and you...
(A) NRM elicits prefusion RSVF cross-reactive serum levels, the quantity of which is two orders of m...
RSV F and G protein specific IgG antibodies were determined by ELISA in sera collected at 3 weeks af...
<p>Mice was immunized twice with Gcfs sublingually or FI-RSV through foot-pad route and then challen...
<p>Mice were (mock-)vaccinated three times either intranasally with BLP-F (○) or PBS (▪) or intramus...
<p>At 90 days post-immunization, mice were challenged with 10<sup>4</sup> PFUs of FMDV C-S8c1 (proce...