<p>(A) RAW264.7 cells were treated with 3 µM celastrol or 10 µM MG132 (or DMSO vehicle) for 30 min, followed by a 10 min treatment with 1 µg/mL LPS. Cellular lysates were prepared and probed for IκB-α or α-tubulin by Western blotting. A representative result of three independent experiments is shown. (B) RAW264.7 cells were treated with indicated concentrations of celastrol or MG132 for 1 h. Cellular lysates were prepared and probed with anti-ubiquitin or anti-α-tubulin. A representative result of three independent experiments is shown. (C) RAW264.7 cells were treated with 10 µM celastrol, 10 µM MG132 and/or 10 µM geldanamycin for 1 h. Cellular lysates were prepared and probed with anti-ubiquitin or anti-α-tubulin. A representative result o...
<p>RAW264.7 or J774A.1 cells were treated for 2 h with LeTx (10<sup>−8 </sup>M PA, 5×10<sup>−10</sup...
<p>The cells were treated with 0 µM, 1 µM, 2 µM, and 4 µM celastrol for the indicated times. The who...
<p><b>A:</b> RA-FLSs were transfected with pGL2-MMP-9WT and <i>Renilla</i> luciferase reporter vecto...
<p>(A) RAW264.7 cells were treated with 3 µM celastrol and/or LeTx (10<sup>−8</sup> M PA and 5×10<su...
Celastrol, a natural substance isolated from plant extracts used in traditional Chinese medicine, ha...
Celastrol, a natural substance isolated from plant extracts used in traditional Chinese medicine, ha...
<p><b>A.</b> Cells were treated with 10 µM ABT-737, 1.25 µM Celastrol and the combination for 24, 48...
<p>RAW 264.7 cells were exposed to oxLDL (80 µg/mL) in the presence or absence of celastrol (50–200 ...
<p>(A). LP-1 cells were treated with 1 µM celastrol for 0 h (lane 1), 12 h (lane 2), 24 h (lane 3), ...
Celastrol is a natural proteasome inhibitor that exhibits promising anti-tumor effects in human mali...
<p>7a. Celastrol enhances HIF-1α expression and induces Akt activation in H1299 cells. H1299 cells w...
Celastrol is a natural proteasome inhibitor that exhibits promising anti-tumor effects in human mali...
BACKGROUND: Bacillus anthracis is the bacterium responsible for causing anthrax. The ability of B. a...
<p>Morphological signatures of celastrol growth inhibitory effects. Cells were treated with various ...
<p>PC-3 cells were treated with various concentrations of celastrol as indicated for 24 hours. The e...
<p>RAW264.7 or J774A.1 cells were treated for 2 h with LeTx (10<sup>−8 </sup>M PA, 5×10<sup>−10</sup...
<p>The cells were treated with 0 µM, 1 µM, 2 µM, and 4 µM celastrol for the indicated times. The who...
<p><b>A:</b> RA-FLSs were transfected with pGL2-MMP-9WT and <i>Renilla</i> luciferase reporter vecto...
<p>(A) RAW264.7 cells were treated with 3 µM celastrol and/or LeTx (10<sup>−8</sup> M PA and 5×10<su...
Celastrol, a natural substance isolated from plant extracts used in traditional Chinese medicine, ha...
Celastrol, a natural substance isolated from plant extracts used in traditional Chinese medicine, ha...
<p><b>A.</b> Cells were treated with 10 µM ABT-737, 1.25 µM Celastrol and the combination for 24, 48...
<p>RAW 264.7 cells were exposed to oxLDL (80 µg/mL) in the presence or absence of celastrol (50–200 ...
<p>(A). LP-1 cells were treated with 1 µM celastrol for 0 h (lane 1), 12 h (lane 2), 24 h (lane 3), ...
Celastrol is a natural proteasome inhibitor that exhibits promising anti-tumor effects in human mali...
<p>7a. Celastrol enhances HIF-1α expression and induces Akt activation in H1299 cells. H1299 cells w...
Celastrol is a natural proteasome inhibitor that exhibits promising anti-tumor effects in human mali...
BACKGROUND: Bacillus anthracis is the bacterium responsible for causing anthrax. The ability of B. a...
<p>Morphological signatures of celastrol growth inhibitory effects. Cells were treated with various ...
<p>PC-3 cells were treated with various concentrations of celastrol as indicated for 24 hours. The e...
<p>RAW264.7 or J774A.1 cells were treated for 2 h with LeTx (10<sup>−8 </sup>M PA, 5×10<sup>−10</sup...
<p>The cells were treated with 0 µM, 1 µM, 2 µM, and 4 µM celastrol for the indicated times. The who...
<p><b>A:</b> RA-FLSs were transfected with pGL2-MMP-9WT and <i>Renilla</i> luciferase reporter vecto...