<div><p>Lung cancer is the leading cause of cancer-related mortality worldwide. Radiotherapy is often applied for treating lung cancer, but it often fails because of the relative non-susceptibility of lung cancer cells to radiation. MicroRNAs (miRNAs) have been reported to modulate the radiosensitivity of lung cancer cells and have the potential to improve the efficacy of radiotherapy. The purpose of this study was to identify a miRNA that can adjust radiosensitivity in lung adenocarcinoma cells. Two lung adenocarcinoma cell lines (CL1-0 and CL1-5) with different metastatic ability and radiosensitivity were used. In order to understand the regulatory mechanisms of differential radiosensitivity in these isogenic tumor cells, both CL1-0 and C...
Background/Aims: Radiotherapy plays a critical role in lung cancer treatment. Radiation can activate...
Radiotherapy (RT) is a widely used and effective non-surgical cancer treatment. However, the mechani...
Abstract Background Radiotherapy is one of the main treatments for esophageal squamous cell carcinom...
Lung cancer is the leading cause of cancer-related mortality worldwide. Radiotherapy is often applie...
Lung cancer is the leading cause of cancer-related mortality worldwide. Radiotherapy is often applie...
Radiotherapy (RT) is a key therapeutic strategy for lung cancer, the most common cause of cancer-rel...
Ionizing radiation (IR) is widely used in cancer treatment and in biological studies. It disrupts ce...
The present study aimed to define the tumor-suppressive role of microRNA-499 (miR-499) in lung cance...
Copyright © 2015 Yan-mei Xu et al. This is an open access article distributed under the Creative Com...
Haining Meng,1 Qiao Huang,1 Xijin Zhang,1 Jiawei Huang,1 Ruowu Shen,1 Bei Zhang21Department of Speci...
MicroRNA-449a is expressed at a low level in several tumors and cancer cell lines, and induces G1 ar...
Background/Aims: Radiation therapy is an important and effective modality for the treatment of non-s...
<div><p>MicroRNA-449a is expressed at a low level in several tumors and cancer cell lines, and induc...
Ionizing radiation (IR) disrupts cellular homeostasis through multiple mechanisms including changes ...
Long Long,1,* Xue Zhang,1,* Jian Bai,2,3 Yizhou Li,4 Xiaolong Wang,5 Yunfeng Zhou11Department of Rad...
Background/Aims: Radiotherapy plays a critical role in lung cancer treatment. Radiation can activate...
Radiotherapy (RT) is a widely used and effective non-surgical cancer treatment. However, the mechani...
Abstract Background Radiotherapy is one of the main treatments for esophageal squamous cell carcinom...
Lung cancer is the leading cause of cancer-related mortality worldwide. Radiotherapy is often applie...
Lung cancer is the leading cause of cancer-related mortality worldwide. Radiotherapy is often applie...
Radiotherapy (RT) is a key therapeutic strategy for lung cancer, the most common cause of cancer-rel...
Ionizing radiation (IR) is widely used in cancer treatment and in biological studies. It disrupts ce...
The present study aimed to define the tumor-suppressive role of microRNA-499 (miR-499) in lung cance...
Copyright © 2015 Yan-mei Xu et al. This is an open access article distributed under the Creative Com...
Haining Meng,1 Qiao Huang,1 Xijin Zhang,1 Jiawei Huang,1 Ruowu Shen,1 Bei Zhang21Department of Speci...
MicroRNA-449a is expressed at a low level in several tumors and cancer cell lines, and induces G1 ar...
Background/Aims: Radiation therapy is an important and effective modality for the treatment of non-s...
<div><p>MicroRNA-449a is expressed at a low level in several tumors and cancer cell lines, and induc...
Ionizing radiation (IR) disrupts cellular homeostasis through multiple mechanisms including changes ...
Long Long,1,* Xue Zhang,1,* Jian Bai,2,3 Yizhou Li,4 Xiaolong Wang,5 Yunfeng Zhou11Department of Rad...
Background/Aims: Radiotherapy plays a critical role in lung cancer treatment. Radiation can activate...
Radiotherapy (RT) is a widely used and effective non-surgical cancer treatment. However, the mechani...
Abstract Background Radiotherapy is one of the main treatments for esophageal squamous cell carcinom...