Metal-Free Oxidative C(sp3)–H Bond Functionalization of Alkanes and Conjugate Addition to Chromones

Transition-Metal-Free Synthesis of Carbonyl-Containing Oxindoles from N‑Arylacrylamides and α‑Diketones via TBHP- or Oxone-Mediated Oxidative Cleavage of C(sp2)–C(sp2) Bonds

Ming-Zhong Zhang (1490209)
Peng-Yi Ji (1490212)
Yu-Feng Liu (744322)
Can-Cheng Guo (579020)

November 2015

Carbonyl-containing oxindoles can be prepared from N-arylacrylamides and α-diketones by TBHP-...

Catalyst-Free Synthesis of Borylated Lactones from Esters via Electrophilic Oxyboration

Darius J. Faizi (1692529)
Adena Issaian (1692535)
Ashlee J. Davis (1692532)
Suzanne A. Blum (1312947)

February 2016

A catalyst-free oxyboration reaction of alkynes is developed. The resulting borylated isocoumarins ...

Molecular Oxygen-Promoted General and Site-Specific Alkylation with Organoboronic Acid

Anbo Ling (6017882)
Lizhi Zhang (1358475)
Ren Xiang Tan (1633183)
Zhong-Quan Liu (1600333)

November 2018

A general alkylating method using organoboronic acid under 1 atm of oxygen is developed. It allows a...

Development of efficient methods for metal-free C–H bond functionalization

Bering, Luis

January 2018

The development of novel and efficient methods for the transition metal-free functionalization of in...

Metal-Free Oxidative Functionalization of C(sp3)–H Bond Adjacent to Oxygen and Radical Addition to Olefins

Wei Zhou (24328)
Ping Qian (1643260)
Jincan Zhao (1632931)
Hong Fang (43040)
Jianlin Han (1408810)
Yi Pan (68170)

March 2015

A DTBP-promoted oxidative functionalization of a C(sp3)–H bond adjacent to oxygen and in...

Metal-Free Oxidative Ipso-Carboacylation of Alkynes: Synthesis of 3‑Acylspiro[4,5]trienones from N‑Arylpropiolamides and Aldehydes

Xuan-Hui Ouyang (1457629)
Ren-Jie Song (1457623)
Yang Li (7082)
Bang Liu (48169)
Jin-Heng Li (1457626)

May 2014

A general and metal-free radical route to synthesis of 3-acylspiro[4,5]trienones is established th...

C(sp)–C(sp3) Bond Formation through Ligand- and Additive-Free CuO-Mediated Decarboxylative Direct Cross-Coupling of Coumarin-/Chromone-3-carboxylic Acids and Terminal Alkynes

Anindita Bhowmick (8975393)
Goutam Brahmachari (1537195)

September 2023

A practical and efficient method for the synthesis of functionalized 4-(aryl-/heteroaryl-ethynyl)chr...

Metal-Free CH–CH-Type Cross-Coupling of Arenes and Alkynes Directed by a Multifunctional Sulfoxide Group

José A. Fernández-Salas (1413298)
Andrew J. Eberhart (1307757)
David J. Procter (1298652)

January 2016

A metal-free CH–CH-type coupling of arenes and alkynes, mediated by a multifunctional sulfoxide dire...

Di-tert-butyl Peroxide-Promoted α‑Alkylation of α‑Amino Carbonyl Compounds by Simple Alkanes

Haibo Peng (1554994)
Jin-Tao Yu (1446985)
Yan Jiang (12139)
Haitao Yang (275233)
Jiang Cheng (1446988)

October 2014

A di-tert butyl peroxide (DTBP)-promoted α-alkylation of α-amino carbonyl compounds by simple...

Base-Promoted Oxidative C–H Functionalization of α‑Amino Carbonyl Compounds under Mild Metal-Free Conditions: Using Molecular Oxygen as the Oxidant

Lei Li (29537)
Yu-Long Zhao (1688344)
Qian Wang (32718)
Tao Lin (124891)
Qun Liu (67203)

January 2015

A base-mediated aerobic oxidation of the C–H bond adjacent to the N-atom of a secondary amine to for...

Oxidant controlled regioselective mono- and di-functionalization reactions of coumarins

Banerjee, Arghya
Santra, Sourav Kumar
Khatun, Nilufa
Ali, Wajid
Patel, Bhisma K.

January 2015

C-3 alkylation of coumarins has been accomplished using cycloalkanes or alkylbenzenes in the presenc...

Cyclic ethers to esters and monoesters to bis-esters with unconventional coupling partners under metal free conditions via sp3 C–H functionalisation

Majji, Ganesh
Guin, Srimanta
Rout, Saroj K.
Behera, Ahalya
Patel, Bhisma K.

January 2014

An efficient metal free oxidative esterification of sp3 C–H bonds (adjacent to an oxygen atom) in si...

Valorization of Small Alkanes by Biocatalytic Oxyfunctionalization

Mahor, Durga (author)
Cong, Zhiqi (author)
Weissenborn, Martin J. (author)
Hollmann, F. (author)
Zhang, Wuyuan (author)

January 2021

The oxidation of alkanes into valuable chemical products is a vital reaction in organic synthesis. T...

Development of base metal-catalyzed C—H functionalization reactions

Griffin, Jennifer Rae

December 2017

For decades, synthetic organic chemists have constructed organic molecules by manipulating functiona...

An efficient oxidative cross-coupling reaction between C-H and N-H Bonds; a transition-metal-free protocol at room temperature

Wu, Y
Kwong, FY
Li, P
Chan, AC

January 2013

A transition-metal-free oxidative coupling of allylic C-H and heterocyclic/aromatic N-H bonds was pe...

Transition-Metal-Free Synthesis of Carbonyl-Containing Oxindoles from N‑Arylacrylamides and α‑Diketones via TBHP- or Oxone-Mediated Oxidative Cleavage of C(sp2)–C(sp2) Bonds

Ming-Zhong Zhang (1490209)
Peng-Yi Ji (1490212)
Yu-Feng Liu (744322)
Can-Cheng Guo (579020)

November 2015

Carbonyl-containing oxindoles can be prepared from N-arylacrylamides and α-diketones by TBHP-...

Catalyst-Free Synthesis of Borylated Lactones from Esters via Electrophilic Oxyboration

Darius J. Faizi (1692529)
Adena Issaian (1692535)
Ashlee J. Davis (1692532)
Suzanne A. Blum (1312947)

February 2016

A catalyst-free oxyboration reaction of alkynes is developed. The resulting borylated isocoumarins ...

Molecular Oxygen-Promoted General and Site-Specific Alkylation with Organoboronic Acid

Anbo Ling (6017882)
Lizhi Zhang (1358475)
Ren Xiang Tan (1633183)
Zhong-Quan Liu (1600333)

November 2018

A general alkylating method using organoboronic acid under 1 atm of oxygen is developed. It allows a...

Development of efficient methods for metal-free C–H bond functionalization

Bering, Luis

January 2018

The development of novel and efficient methods for the transition metal-free functionalization of in...

Metal-Free Oxidative Functionalization of C(sp3)–H Bond Adjacent to Oxygen and Radical Addition to Olefins

Wei Zhou (24328)
Ping Qian (1643260)
Jincan Zhao (1632931)
Hong Fang (43040)
Jianlin Han (1408810)
Yi Pan (68170)

March 2015

A DTBP-promoted oxidative functionalization of a C(sp3)–H bond adjacent to oxygen and in...

Metal-Free Oxidative Ipso-Carboacylation of Alkynes: Synthesis of 3‑Acylspiro[4,5]trienones from N‑Arylpropiolamides and Aldehydes

Xuan-Hui Ouyang (1457629)
Ren-Jie Song (1457623)
Yang Li (7082)
Bang Liu (48169)
Jin-Heng Li (1457626)

May 2014

A general and metal-free radical route to synthesis of 3-acylspiro[4,5]trienones is established th...

C(sp)–C(sp3) Bond Formation through Ligand- and Additive-Free CuO-Mediated Decarboxylative Direct Cross-Coupling of Coumarin-/Chromone-3-carboxylic Acids and Terminal Alkynes

Anindita Bhowmick (8975393)
Goutam Brahmachari (1537195)

September 2023

A practical and efficient method for the synthesis of functionalized 4-(aryl-/heteroaryl-ethynyl)chr...

Metal-Free CH–CH-Type Cross-Coupling of Arenes and Alkynes Directed by a Multifunctional Sulfoxide Group

José A. Fernández-Salas (1413298)
Andrew J. Eberhart (1307757)
David J. Procter (1298652)

January 2016

A metal-free CH–CH-type coupling of arenes and alkynes, mediated by a multifunctional sulfoxide dire...

Di-tert-butyl Peroxide-Promoted α‑Alkylation of α‑Amino Carbonyl Compounds by Simple Alkanes

Haibo Peng (1554994)
Jin-Tao Yu (1446985)
Yan Jiang (12139)
Haitao Yang (275233)
Jiang Cheng (1446988)

October 2014

A di-tert butyl peroxide (DTBP)-promoted α-alkylation of α-amino carbonyl compounds by simple...

Base-Promoted Oxidative C–H Functionalization of α‑Amino Carbonyl Compounds under Mild Metal-Free Conditions: Using Molecular Oxygen as the Oxidant

Lei Li (29537)
Yu-Long Zhao (1688344)
Qian Wang (32718)
Tao Lin (124891)
Qun Liu (67203)

January 2015

A base-mediated aerobic oxidation of the C–H bond adjacent to the N-atom of a secondary amine to for...

Oxidant controlled regioselective mono- and di-functionalization reactions of coumarins

Banerjee, Arghya
Santra, Sourav Kumar
Khatun, Nilufa
Ali, Wajid
Patel, Bhisma K.

January 2015

C-3 alkylation of coumarins has been accomplished using cycloalkanes or alkylbenzenes in the presenc...

Cyclic ethers to esters and monoesters to bis-esters with unconventional coupling partners under metal free conditions via sp3 C–H functionalisation

Majji, Ganesh
Guin, Srimanta
Rout, Saroj K.
Behera, Ahalya
Patel, Bhisma K.

January 2014

An efficient metal free oxidative esterification of sp3 C–H bonds (adjacent to an oxygen atom) in si...

Valorization of Small Alkanes by Biocatalytic Oxyfunctionalization

Mahor, Durga (author)
Cong, Zhiqi (author)
Weissenborn, Martin J. (author)
Hollmann, F. (author)
Zhang, Wuyuan (author)

January 2021

The oxidation of alkanes into valuable chemical products is a vital reaction in organic synthesis. T...

Development of base metal-catalyzed C—H functionalization reactions

Griffin, Jennifer Rae

December 2017

For decades, synthetic organic chemists have constructed organic molecules by manipulating functiona...

An efficient oxidative cross-coupling reaction between C-H and N-H Bonds; a transition-metal-free protocol at room temperature

Wu, Y
Kwong, FY
Li, P
Chan, AC

January 2013

A transition-metal-free oxidative coupling of allylic C-H and heterocyclic/aromatic N-H bonds was pe...

Transition-Metal-Free Synthesis of Carbonyl-Containing Oxindoles from N‑Arylacrylamides and α‑Diketones via TBHP- or Oxone-Mediated Oxidative Cleavage of C(sp2)–C(sp2) Bonds

Ming-Zhong Zhang (1490209)
Peng-Yi Ji (1490212)
Yu-Feng Liu (744322)
Can-Cheng Guo (579020)

November 2015

Carbonyl-containing oxindoles can be prepared from N-arylacrylamides and α-diketones by TBHP-...

Catalyst-Free Synthesis of Borylated Lactones from Esters via Electrophilic Oxyboration

Darius J. Faizi (1692529)
Adena Issaian (1692535)
Ashlee J. Davis (1692532)
Suzanne A. Blum (1312947)

February 2016

A catalyst-free oxyboration reaction of alkynes is developed. The resulting borylated isocoumarins ...

Molecular Oxygen-Promoted General and Site-Specific Alkylation with Organoboronic Acid

Anbo Ling (6017882)
Lizhi Zhang (1358475)
Ren Xiang Tan (1633183)
Zhong-Quan Liu (1600333)

November 2018

A general alkylating method using organoboronic acid under 1 atm of oxygen is developed. It allows a...

Metal-Free Oxidative C(sp<sup>3</sup>)–H Bond Functionalization of Alkanes and Conjugate Addition to Chromones

Abstract

Extracted data

Related items

Related items