PATHOLOGY REVIEW Neuropathology

  • For The Neuroradiologist Plaques
  • Tangles
  • N. Cairns
  • K. Vo
  • D. M. Holtzman
ORKG logo View in ORKG
Publication date
December 2014

Abstract

SUMMARY: Histologically identified intracellular and extracellular inclusions and structures often pro-vide a tissue diagnosis of a specific disease process. Moreover, these deposits may provide clues about the pathogenesis of the disease in which they are found. Two distinctive structures seen within the brains of patients clinically diagnosed with dementia of the Alzheimer type are extracellular plaques and intracellular neurofibrillary tangles. The purpose of this report is to review the significance of plaques and neurofibrillary tangles in the context of Alzheimer disease. Histologically identified cellular deposits often provide atissue diagnosis as well as clues about the pathogenesis of the disease that they represent. Two distincti...

Extracted data

We use cookies to provide a better user experience.