Add to ORKGhemochromatosis may be associated with an increased risk of cardiovascular disease. We examined the relation between two HFE mutations (C282Y and H63D), indicators of iron ho-meostasis, and the prevalence of coronary heart disease in a large population of white adults. SUBJECTS AND METHODS: We conducted a cross-sectional study of 30,916 white adults aged 25 to 98 years who attended a health appraisal center and underwent screening for HFE mu-tations. Coronary heart disease and cardiovascular risk factors were ascertained by questionnaire and medical records. RESULTS: Overall, 12 % (1798/15,362) of men and 7 % (1074/ 15,554) of women had a history of coronary heart disease. Of 10 HFE genotypes tested (five genotypes by sex), only men with th...
BACKGROUND: The C282Y mutation of the hemochromatosis (HFE)-gene increases body iron status. Among C...
Background The C282Y mutation of the hemochromatosis (HFE)-gene increases body iron status. Among Ca...
Hereditary hemochromatosis is a common inherited disorder of the iron metabolism. Screening studies ...
Whether mutations in the hemochromatosis (HFE) gene increase cardiovascular disease risk is still un...
he purpose of the present study is to examine HFE gene mutations in relation to newly diagnosed (inc...
BACKGROUND: Whether mutations in the hemochromatosis (HFE) gene increase cardiovascular disease ris...
The identification of mutations in the haemochromatosis gene (HFE) (C282Y and H63D) provides the uni...
Background: Increased iron stores and haemochromatosis gene mutations may be risk factors for corona...
BACKGROUND: Although heterozygosity for the C282Y mutation in the HFE gene has been associated with ...
There is interest in the role of iron in age-related diseases such as atherosclerosis. Tissue iron d...
Although iron can catalyze the production of free radicals involved in LDL lipid peroxidation, the c...
Hereditary hemochromatosis (HH) is a disorder of iron accumulation in tissues, which is related to c...
The C282Y and H63D mutations in the HFE gene are important causes of hemochromatosis. In the elderly...
Recent studies have raised questions about the long-term health risks for individuals with mutations...
Abstract Hereditary hemochromatosis (HH) is a common autosomal recessive disorder estimated to affec...
BACKGROUND: The C282Y mutation of the hemochromatosis (HFE)-gene increases body iron status. Among C...
Background The C282Y mutation of the hemochromatosis (HFE)-gene increases body iron status. Among Ca...
Hereditary hemochromatosis is a common inherited disorder of the iron metabolism. Screening studies ...
Whether mutations in the hemochromatosis (HFE) gene increase cardiovascular disease risk is still un...
he purpose of the present study is to examine HFE gene mutations in relation to newly diagnosed (inc...
BACKGROUND: Whether mutations in the hemochromatosis (HFE) gene increase cardiovascular disease ris...
The identification of mutations in the haemochromatosis gene (HFE) (C282Y and H63D) provides the uni...
Background: Increased iron stores and haemochromatosis gene mutations may be risk factors for corona...
BACKGROUND: Although heterozygosity for the C282Y mutation in the HFE gene has been associated with ...
There is interest in the role of iron in age-related diseases such as atherosclerosis. Tissue iron d...
Although iron can catalyze the production of free radicals involved in LDL lipid peroxidation, the c...
Hereditary hemochromatosis (HH) is a disorder of iron accumulation in tissues, which is related to c...
The C282Y and H63D mutations in the HFE gene are important causes of hemochromatosis. In the elderly...
Recent studies have raised questions about the long-term health risks for individuals with mutations...
Abstract Hereditary hemochromatosis (HH) is a common autosomal recessive disorder estimated to affec...
BACKGROUND: The C282Y mutation of the hemochromatosis (HFE)-gene increases body iron status. Among C...
Background The C282Y mutation of the hemochromatosis (HFE)-gene increases body iron status. Among Ca...
Hereditary hemochromatosis is a common inherited disorder of the iron metabolism. Screening studies ...