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Immediate function of four zygomatic implants: a one-year report of a prospective study Key words atrophic maxilla, immediate loading, zygomatic implants Purpose: To evaluate the clinical outcome of maxillary prostheses supported by four immediately loaded zygomatic implants after one year of function. Materials and methods: Seventeen patients were consecutively included and followed up to one year after prosthetic loading. Patients had severely atrophic maxillae (Cawood and Howell classification C-VI and D-V or D-VI) and were rehabilitated using four zygomatic immediately loaded implants, two in each zygoma bone. Outcome measures were success rates of the prostheses, of the zygomatic implants, complications and oral health-related quality of life (OHRQoL). Results: No patients dropped out. No zygomatic implants were lost, although one implant could not be used because it was placed in an unfavourable position. The orbital cavity was penetrated during the drilling procedure in one patient with no relevant clinical consequences. One patient experienced an infection followed by a fistula in one zygomatic implant, which was successfully treated. The aver-age score from the OHIP-14 questionnaire was 3.4, which is similar to that of the general population