Copyright © 2011 Sadagopan Magesh et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Identification of selective influenza viral sialidase inhibitors is highly desirable in order to minimize or avoid the adverse effects due to the possible inhibition of endogenous human sialidases. We recently reported the evaluation of C9 N-acyl Neu5Ac2en mimetics as probes for human sialidases. Herein, we describe the in vitro activity of the same set of C9N-acyl Neu5Ac2enmimetics against sialidases expressed by influenza virus A/PR/8/34 (H1N1), A/Memphis/1/72 (H3N2), and A/Duck/313/78 (...
Background: Influenza generally known as flu is due to viruses that contaminate the respiratory regi...
[[abstract]]Influenza is an annual seasonal epidemic that has continually drawn public attentions, d...
As a new strain of virus emerged in 2013, avian influenza A (H7N9) virus is a threat to the public h...
Influenza virus sialidase has an essential role in the virus ’ life cycle. Two distinct groups of in...
Due to the recent emergence of avian flu, the possibility of a pandemic wave of life-threatening flu...
Copyright © 2015 Zekun Liu et al. This is an open access article distributed under the Creative Comm...
Influenza virus sialidase has an essential role in the virus’ life cycle. Two distinct groups of inf...
The demand for novel anti-influenza drugs persists, which is highlighted by the recent pandemics of ...
In light of the recent novel H1N1 virus epidemic, virus resistance to currently approved antiviral m...
This review will give an overview of the design process behind the development of sialidase inhibito...
Computational molecular docking provides an efficient and innovative approach to examine small molec...
International audienceInfluenza virus sialidase has an essential role in the virus' life cycle. Two ...
none5noSialic acids are involved in a plethora of important biological events; among these the most ...
With the global spread of the pandemic H1N1 and the ongoing pandemic potential of the H5N1 subtype, ...
Global infections with viruses belonging to the Paramyxoviridae, such as Newcastle disease virus (ND...
Background: Influenza generally known as flu is due to viruses that contaminate the respiratory regi...
[[abstract]]Influenza is an annual seasonal epidemic that has continually drawn public attentions, d...
As a new strain of virus emerged in 2013, avian influenza A (H7N9) virus is a threat to the public h...
Influenza virus sialidase has an essential role in the virus ’ life cycle. Two distinct groups of in...
Due to the recent emergence of avian flu, the possibility of a pandemic wave of life-threatening flu...
Copyright © 2015 Zekun Liu et al. This is an open access article distributed under the Creative Comm...
Influenza virus sialidase has an essential role in the virus’ life cycle. Two distinct groups of inf...
The demand for novel anti-influenza drugs persists, which is highlighted by the recent pandemics of ...
In light of the recent novel H1N1 virus epidemic, virus resistance to currently approved antiviral m...
This review will give an overview of the design process behind the development of sialidase inhibito...
Computational molecular docking provides an efficient and innovative approach to examine small molec...
International audienceInfluenza virus sialidase has an essential role in the virus' life cycle. Two ...
none5noSialic acids are involved in a plethora of important biological events; among these the most ...
With the global spread of the pandemic H1N1 and the ongoing pandemic potential of the H5N1 subtype, ...
Global infections with viruses belonging to the Paramyxoviridae, such as Newcastle disease virus (ND...
Background: Influenza generally known as flu is due to viruses that contaminate the respiratory regi...
[[abstract]]Influenza is an annual seasonal epidemic that has continually drawn public attentions, d...
As a new strain of virus emerged in 2013, avian influenza A (H7N9) virus is a threat to the public h...