Natrural substances with toxic and allergic activity

Charles University, Faculty of Pharmacy in Hradec Králové Department of Pharmacognosy Supervisor: doc. PharmDr. Lenka Tůmová, CSc. Student: Vendula Rapiová Title of Thesis: Natural substances with toxic and allergic activity Keywords: medicinal plant, allergy, side effects, toxicity The connection between herbs and mankind dates to early ages and without discussion herbal remedies were the first one to put in use. We observe significant increase of herbal remedies used in paediatric patients in last decades. The goal of this work was set to examine available information about herbal safety. The list of herbs that are dangerous or inappropriate to use in children age was made. The herbs were grouped into simple classification system of herbal safety. In addition to chapters describing herbal safety the work contains knowledge about their general use in paediatrics phytotherapy, the pros and cons of their use. To gather the data of web research and scientific literature were employed. The analysed data were published between 1968-2017 and were collected using PubMed, ScienceDirect and Google Scholar. The rate of herbal safety is classified into five specific groups - A, B, C, S and X. The analysis of results shows that the biggest group with the most represented samples in class was the class C with..