The circadian system controls the timing of behavioral and physiological processes in most organisms with a period of about 24 h. In mammals, the circadian system consists of the central oscillator in the suprachiasmatic nuclei (SCN) and peripheral oscillators located in numerous organs such as the liver, heart, lung, muscles, intestines etc. Peripheral oscillators are cell-autonomous, they could also work independently of the SCN entrained by a feeding cycle. The misalignment of the endogenous timekeeping system, due to e.g. irregular daily schedule or shiftwork, may lead to the development of severe diseases including sleep disorders, gastrointestinal (GI) problems and various types of cancer. Therefore, understanding the molecular mechan...
The circadian system is a mechanism designed to generate circadian time and to synchronize it with t...
The mammalian circadian system, which is comprised of multiple cellular clocks located in the organs...
Copyright © 2011 Carolina Escobar et al. This is an open access article distributed under the Creati...
Mammalian circadian clock in peripheral organs, molecular mechanism and entrainment The circadian sy...
The circadian system is an important coordinator of physiological functions of a mammalian organism....
The circadian system temporally controls behavioral and physiological processes in most organisms so...
One of the attributes common to almost all living organisms is an ability to generate and maintain e...
Malfunction of the circadian timing system may result in cardiovascular and metabolic diseases, and ...
Under constant conditions, many biological processes repeat regularly with a period about 24 hour, i...
The ability to sense 24-hour cycles in external environment and to adapt to them is present in a gre...
<div><p>Malfunction of the circadian timing system may result in cardiovascular and metabolic diseas...
The inner circadian timekeeping system rules all physiological proccesses that repeat in our body re...
The muti-oscillatory circadian system consists of the suprachiasmatic clock (SCN) the master clock, ...
Many physiological processes in organisms from bacteria to man are rhythmic, and some of these are c...
Many physiological processes in organisms from bacteria to man are rhythmic, and some of these are c...
The circadian system is a mechanism designed to generate circadian time and to synchronize it with t...
The mammalian circadian system, which is comprised of multiple cellular clocks located in the organs...
Copyright © 2011 Carolina Escobar et al. This is an open access article distributed under the Creati...
Mammalian circadian clock in peripheral organs, molecular mechanism and entrainment The circadian sy...
The circadian system is an important coordinator of physiological functions of a mammalian organism....
The circadian system temporally controls behavioral and physiological processes in most organisms so...
One of the attributes common to almost all living organisms is an ability to generate and maintain e...
Malfunction of the circadian timing system may result in cardiovascular and metabolic diseases, and ...
Under constant conditions, many biological processes repeat regularly with a period about 24 hour, i...
The ability to sense 24-hour cycles in external environment and to adapt to them is present in a gre...
<div><p>Malfunction of the circadian timing system may result in cardiovascular and metabolic diseas...
The inner circadian timekeeping system rules all physiological proccesses that repeat in our body re...
The muti-oscillatory circadian system consists of the suprachiasmatic clock (SCN) the master clock, ...
Many physiological processes in organisms from bacteria to man are rhythmic, and some of these are c...
Many physiological processes in organisms from bacteria to man are rhythmic, and some of these are c...
The circadian system is a mechanism designed to generate circadian time and to synchronize it with t...
The mammalian circadian system, which is comprised of multiple cellular clocks located in the organs...
Copyright © 2011 Carolina Escobar et al. This is an open access article distributed under the Creati...