Incidence of Methicillin-Resistant Staphylococcus aureus in University Hospital Hradec Králové 2008-2010.

Charles University in Prague Faculty of Pharmacy in Hradec Králové Department of Biological and medical Sciences Candidate: Bc. Hana Vaculíková Supervisor: MUDr. Pavla Paterová Title of diploma thesis: Incidence of Methicillin-Resistant Staphylococcus aureus in University Hospital Hradec Králové 2008-2010 Strains of methicillin-resistant Staphylococcus aureus (MRSA) are a significant cause of nosocomial infections. Their epidemiology keeps changing and MRSA infections are increasingly more frequent also among common population, which trend has become most noticeable in the USA. S. aureus can be generally found on skin or mucosae of healthy people, however its drug-resistant strains constitute a serious global problem, as the treatment of such infections is complicated and expensive. The practical part deals with the occurrence of MRSA at the University hospital in Hradec Králové in the years 2008 - 2010 and strives to verify the theory of a long-term or even life-long latent MRSA infections in patients that have already been diagnosed with MRSA. The analysis was focused on occurrence in various types of material, occurrence on particular hospital departments, age of the patients and diagnosis of MRSA in a time-scale. In the years 2008-2009 the most frequently positive material were samples from the..