Evaluation of the Prediction Equations for Resting Energy Expenditure in Critically ill Patients

Charles University in Prague, Faculty of Pharmacy in Hradec Králové Department of Biological and Medical Sciences Candidate Mgr.Veronika Tichá Consultant PharmDr. Miloslav Hronek, Ph.D. Title of Thesis Evaluation of the prediction equations for resting energy expenditure in critically ill patients The inaccurate prediction of nutritional requirements of critically ill patients can cause overfeeding or underfeeding. It may lead to deceleration of repair processes, failure of organ function to fatal consequences. Indirect calorimetry is the most accurate method for assessment of energy requirements, but it not available in every intensive care unit. Thus, the purpose of this study was to evaluate accuracy of the prediction equations in critically ill patients and compare them with REE measured by indirect calorimetry. The study took place in the intensive care unit at FN HK during 8 months. Twenty patients were examined (mean age 35 years ± 16 years, BMI 27,8 kg/m2 ± 8,4 kg/m2 ). Measure of resting energy expenditure by indirect calorimetry were compare with REE calculate by using different nineteen prediction equations. Resting energy expenditure was on average 2166 kcal/d ± 552 kcal/d. Only these equations - Ireton-Liepa (2239 kcal/d ± 341 kcal/d; P = 0,6152; 103 % MEE), Ireton-Jones 1997 (2266..