Add to ORKGThe first part of the bachelor thesis deals with enantioselective allylation of thiophene-2- carbaldehyde to the corresponding chiral homoallylic alcohol by using chiral Lewis bases as catalysts. The highest asymmetric induction achieved was 97 % ee. The second part concerns application of the prepared chiral homoallylic alcohol as the crucial intermediate for synthesis of antidepressant (S)-duloxetine. Key words enantioselective, allylation, Lewis base, thiophene-2-carbaldehyde, duloxetin
This thesis describes an investigation on the synthesis of chiral 1,2,3,4-tetrahydroisoquinoline-bas...
This bachelor thesis is focused on the application of organocatalytic approach for the synthesis of ...
Since 2000 the organocatalytic synthesis has developed massively in a third pillar of asymmetric syn...
A unifying topic in this thesis is the development of routes to optically active compounds. The impo...
The use of chiral sulfoxides as Lewis base catalysts in the allylation of aldehydes with allyltrichl...
The main subject of this thesis is synthesis of chiral diene systems via Ring Closing Enyne Metathes...
Duloxitine is a serotonin-norepinephrine reuptake inhibitor used in the treatment of depression and ...
The implementation of chiral centres within biologically active compounds has been a perplexing yet...
Chiral dinitrones were synthesized by condensation of a C2-symmetrical chiral dihydroxylamine with v...
This bachelor thesis deals with the preparation of chiral secondary amines, which are used as cataly...
A unifying topic in this thesis is the development of routes to optically active compounds. The impo...
This bachelor thesis is focused on stereoselective preparation of spiro compounds using organocataly...
This diploma thesis deals with the use of organocatalysis in an asymmetric allylic substitution reac...
The subject of this PhD thesis is in the synthesis of new chiral amino alcohols and diamines using s...
This dissertation describes new methods of asymmetric synthesis of diastereomeric and enantiomeric p...
This thesis describes an investigation on the synthesis of chiral 1,2,3,4-tetrahydroisoquinoline-bas...
This bachelor thesis is focused on the application of organocatalytic approach for the synthesis of ...
Since 2000 the organocatalytic synthesis has developed massively in a third pillar of asymmetric syn...
A unifying topic in this thesis is the development of routes to optically active compounds. The impo...
The use of chiral sulfoxides as Lewis base catalysts in the allylation of aldehydes with allyltrichl...
The main subject of this thesis is synthesis of chiral diene systems via Ring Closing Enyne Metathes...
Duloxitine is a serotonin-norepinephrine reuptake inhibitor used in the treatment of depression and ...
The implementation of chiral centres within biologically active compounds has been a perplexing yet...
Chiral dinitrones were synthesized by condensation of a C2-symmetrical chiral dihydroxylamine with v...
This bachelor thesis deals with the preparation of chiral secondary amines, which are used as cataly...
A unifying topic in this thesis is the development of routes to optically active compounds. The impo...
This bachelor thesis is focused on stereoselective preparation of spiro compounds using organocataly...
This diploma thesis deals with the use of organocatalysis in an asymmetric allylic substitution reac...
The subject of this PhD thesis is in the synthesis of new chiral amino alcohols and diamines using s...
This dissertation describes new methods of asymmetric synthesis of diastereomeric and enantiomeric p...
This thesis describes an investigation on the synthesis of chiral 1,2,3,4-tetrahydroisoquinoline-bas...
This bachelor thesis is focused on the application of organocatalytic approach for the synthesis of ...
Since 2000 the organocatalytic synthesis has developed massively in a third pillar of asymmetric syn...