Add to ORKGBlood flukes of the genus Schistosoma cause schistosomiasis, one of the most serious parasitic diseases. Cathepsin C (EC 3.4.14.1) is a digestive enzyme of the blood flukes and a potential drug target. This cysteine protease has not been studied in detail yet. In this thesis, cathepsin C activity was detected in the extract of adult blood flukes S. mansoni and S. japonicum. Inhibitory specificity of these enzymes was determined using of set of selective inhibitors of mammalian cathepsins. Cathepsins C were visualized on SDS-PAGE gels with fluorescent proteomic probe. Furthermore, recombinant cathepsin C of S. mansoni (SmCC) was prepared by homologous expression in the yeast Pichia pastoris. (In Czech
Schistosomes express a variety of aspartyl proteases (APs) with distinct roles in the helminth patho...
Schistosomes utilise haemoglobin from ingested host erythrocytes as their main source of amino acids...
The blood fluke Schistosoma mansoni and the hard tick Ixodes ricinus produce an aspartic protease ca...
Blood flukes of the genus Schistosoma cause schistosomiasis, a serious parasitic disease occurring i...
This report presents the deduced amino acid sequence of a novel cathepsin L proteinase from Schistos...
A cDNA encoding preprocathepsin C was isolated from adults of the asian blood fluke Schistosoma japo...
Based on substrate preferences, cercariae of Schistosoma mansoni were seen to express both cathepsin...
The liver fluke, Fasciola hepatica, is one of the most important parasites of livestock, and it also...
Ticks are globally important parasites involved in transmission of a wide variety of infectious agen...
BackgroundBlood flukes of the genus Schistosoma are platyhelminth parasites that infect 200 million ...
Ticks are globally important parasites involved in transmission of a wide variety of infectious agen...
AbstractA transcriptional product of a gene encoding cathepsin B-like peptidase in the bird schistos...
Blood flukes of the genus Schistosoma are parasitic trematodes that cause schistosomiasis, a serious...
Adult Schistosoma mansoni parasites synthesize and secrete both cathepsin L and cathepsin B cysteine...
Schistosomes express a variety of aspartyl proteases (APs) with distinct roles in the helminth patho...
Schistosomes express a variety of aspartyl proteases (APs) with distinct roles in the helminth patho...
Schistosomes utilise haemoglobin from ingested host erythrocytes as their main source of amino acids...
The blood fluke Schistosoma mansoni and the hard tick Ixodes ricinus produce an aspartic protease ca...
Blood flukes of the genus Schistosoma cause schistosomiasis, a serious parasitic disease occurring i...
This report presents the deduced amino acid sequence of a novel cathepsin L proteinase from Schistos...
A cDNA encoding preprocathepsin C was isolated from adults of the asian blood fluke Schistosoma japo...
Based on substrate preferences, cercariae of Schistosoma mansoni were seen to express both cathepsin...
The liver fluke, Fasciola hepatica, is one of the most important parasites of livestock, and it also...
Ticks are globally important parasites involved in transmission of a wide variety of infectious agen...
BackgroundBlood flukes of the genus Schistosoma are platyhelminth parasites that infect 200 million ...
Ticks are globally important parasites involved in transmission of a wide variety of infectious agen...
AbstractA transcriptional product of a gene encoding cathepsin B-like peptidase in the bird schistos...
Blood flukes of the genus Schistosoma are parasitic trematodes that cause schistosomiasis, a serious...
Adult Schistosoma mansoni parasites synthesize and secrete both cathepsin L and cathepsin B cysteine...
Schistosomes express a variety of aspartyl proteases (APs) with distinct roles in the helminth patho...
Schistosomes express a variety of aspartyl proteases (APs) with distinct roles in the helminth patho...
Schistosomes utilise haemoglobin from ingested host erythrocytes as their main source of amino acids...
The blood fluke Schistosoma mansoni and the hard tick Ixodes ricinus produce an aspartic protease ca...