Spermatogenesis, Classification and Evaluation of Sperm Morphology for Assisted Reproduction.

Spermatogenesis, Classification and Evaluation of Sperm Morphology for Assisted Reproduction Abstract Sperm quality has an important role in determining male fertility. There is an increasing amount of couples searching for assisted reproduction due to the increasing decline in quality of sperm. Morphology of sperm is one of the factors influencing male fertility and defects in sperm morphology are the main subject of many studies. Mammalian sperm are formed during spermatogenesis and defects in spermatogenesis may cause severe defects in sperm morphology. Defects of a sperm head, as well as a mid- piece and principal piece of sperm tail sperm can have a serious impact on fertilizing ability of sperm and it is, therefore, necessary in some cases to use methods of assisted reproduction due to morphological abnormalities. The main objects of this thesis were to describe spermatogenesis, normal and pathogenic sperm morphology and evaluate the use and outcome of assisted reproduction methods based on sperm morphology and apply the evaluation in selecting the best method of assisted reproduction. To some extent, sperm morphology influences the outcome of assisted reproduction and it is a significant factor in predicting fertilization, pregnancy and embryo cleavage/development rate. In some cases of severe..