Treatment Success Sulphonylureas in Type 2 Diabetes

Charles University in Prague Faculty of Pharmacy in Hradec Králové Department of Pharmacology and Toxicology Candidate: Mgr. Michaela Černá Consultant: PharmDr. Marie Vopršalová, CSc Title of Thesis: Treatment success sulphonylureas in type 2 diabetes This construed examination paper deals with the analysis of the effectiveness of treatment with peroral antidiabetic drugs - sulfphonylurea derivatives for 2nd type diabetics. In the theoretical section there are summarized the basic principles of screening and diagnosis of 2nd type diabetes. There is outlined algorithm of the selection of treatment and briefly described individual classes of peroral antidiabetic drugs. There is also a mention of other possibilities for pharmacotherapy of diabetes. More attention is given to peroral diabetic drugs from a group of sulfonylureas derivatives, where individual knowledge are supported by scientific studies. The aim of experimental part of study was to follow experiences with sulfphonylurea derivatives therapy on a group of patients treated in the medical facility Dům zdraví Havířov. There was followed the advantageousness of therapy and reasons for laying off the particular medicinal substances. I found that most patients had experience with glimepiride, and combinations of peroral antidiabetic drugs from..