Electro-migration and chromatographic methods of analysis of quaternary ammonium

Charles University in Prague Faculty of Pharmacy in Hradec Králové Department of Analytical Chemistry Candidate: Jana Kunzová Supervisor: Doc. RNDr. Miroslav Polášek, CSc. Title of the diploma thesis: Electro-migration and chromatographic methods of analysis of quaternary ammonium compounds Quaternary ammonium compounds are widely used in different spheres of life. They are employed as surfactants, pesticides, herbicides, drugs, disinfectants or components of cosmetic products. These compounds have miscellaneous structures. Wide application of these compounds requires development of analytical methods for their monitoring in foods, environment, sewage water, biological samples etc. This essay presents an overview of published electro-migration and chromatographic methods of analysis of quaternary ammonium compounds. Simultaneously this review allows to compare both methods, their advantages and disadvantages. Relevant information was obtained from literature published in the years 1995 - 2010. The literature search was realized through the SceinceDirect and PubMed databases