DOLEŽAL Rafael: Quantitative relationships between the structure and antimycobacterial activity of selected potential antituberculotics. Hradec Králové: Faculty of Pharmacy in Hradec Králové, Charles University in Prague, 2008, 274 pp. Ph.D. Thesis. The Ph.D. thesis deals with analysis of quantitative relationships between the structure and antimycobacterial activity (QSAR) of four structural classes of potential antituberculotics - derivatives of N-phenylcarbamic acid esters, derivatives of 1-phenyl-1H-tetrazole-5-thiol, derivatives of salicylamides and derivatives of salicylthioamides. In total, 600 computer models of different compounds were created. 204 of them, after conformational analysis in HyperChem 7.52 and geometric optimization ...
A quantitative structure–activity relationship (QSAR) of a library of eighteen cationic anthraquinon...
Graduation date: 1987Nalidixic acid and its derivatives act through inhibition of\ud bacterial DNA g...
Worldwide, tuberculosis (TB) is the leading cause of death among curable infectious diseases. Multid...
The incidence of tuberculosis infections that are resistant to conventional drug therapy has risen ...
Abstract—The antimycobacterial activity of nitro / acetamido alkenol derivatives and chloro / amino ...
In order to produce a desired physiological effect, substances have to cross cell membranes. The abi...
Objectives: In order to select new drugs and to predict their in vitro activity against Mycobacteriu...
Charles University, Faculty of Pharmacy in Hradec Králové Department of Organic and Bioorganic Chemi...
Nowadays, many people still fall victim to tuberculosis, the disease that has a worldwide spreading...
Antitubercular activity of 5-nitrofuran-2-yl Derivatives series were subjected to Quantitative Struc...
To develop the quantitative structure–activity relationship (QSAR) for predicting the anticonvulsant...
<p>Background</p> <p>Essential oils and their constituents are commonly known for their antibacteria...
A quantitative structure–activity relationship (QSAR) of a library of eighteen cationic anthraquinon...
A quantitative structure–activity relationship (QSAR) of a library of eighteen cationic anthraquinon...
Development of more potent antituberculosis agents is as a result of emergence of multidrug resistan...
A quantitative structure–activity relationship (QSAR) of a library of eighteen cationic anthraquinon...
Graduation date: 1987Nalidixic acid and its derivatives act through inhibition of\ud bacterial DNA g...
Worldwide, tuberculosis (TB) is the leading cause of death among curable infectious diseases. Multid...
The incidence of tuberculosis infections that are resistant to conventional drug therapy has risen ...
Abstract—The antimycobacterial activity of nitro / acetamido alkenol derivatives and chloro / amino ...
In order to produce a desired physiological effect, substances have to cross cell membranes. The abi...
Objectives: In order to select new drugs and to predict their in vitro activity against Mycobacteriu...
Charles University, Faculty of Pharmacy in Hradec Králové Department of Organic and Bioorganic Chemi...
Nowadays, many people still fall victim to tuberculosis, the disease that has a worldwide spreading...
Antitubercular activity of 5-nitrofuran-2-yl Derivatives series were subjected to Quantitative Struc...
To develop the quantitative structure–activity relationship (QSAR) for predicting the anticonvulsant...
<p>Background</p> <p>Essential oils and their constituents are commonly known for their antibacteria...
A quantitative structure–activity relationship (QSAR) of a library of eighteen cationic anthraquinon...
A quantitative structure–activity relationship (QSAR) of a library of eighteen cationic anthraquinon...
Development of more potent antituberculosis agents is as a result of emergence of multidrug resistan...
A quantitative structure–activity relationship (QSAR) of a library of eighteen cationic anthraquinon...
Graduation date: 1987Nalidixic acid and its derivatives act through inhibition of\ud bacterial DNA g...
Worldwide, tuberculosis (TB) is the leading cause of death among curable infectious diseases. Multid...