Treatment of asthma bronchiale

Topic: Therapy of asthma bronchiale Author: Martina Čudová Bronchial asthma is a lifetime chronical inflammatory disease of the airways. Chronical inflammation is linked to bronchial hyperreaktivity and both lead to reversible and variable obstruction of airways. The prevalence of this disease has been increasing in recent years, mainly in children and teenagers, where asthma becomes the most frequent disorder. Asthma isn't curable, but thanks to opportune diagnosis and correctly configured treatment, the patient can be absolutely without difficulties. Conversely, untreated asthma leads to irreversible functional environments, which deteriorate the patient's performance and his quality of life. An important part of the treatment is preventive proceding, its goal is the avoidance of the patient's contact with triggers. Pharmacotherapy is devided into treatment of exacerbation, when alleviation drugs are used, primarily inhalational rapid acting β2-agonists and long-term anti-inflammatory therapy, there are drugs of choice inhalational kortikosteroids. The latest substances include the antileukotriens and monoclonal antibody against IgE (omalizumab)