Intrahepatic bile ducts develop according to a new mode of tubulogenesis regulated by the transcription factor SOX9.
- Antoniou, Aline
- Raynaud, Peggy
- Cordi, Sabine
- Zong, Yiwei
- Tronche, François
- Stanger, Ben Z
- Jacquemin, Patrick
- Pierreux, C.
- Clotman, Frederic
- Lemaigre, F.
Publication date
June 2009
DOI Publisher
Elsevier BV ISSN
0016-5085 Citation count (estimate)
175Abstract
A number of diseases are characterized by defective formation of the intrahepatic bile ducts. In the embryo, hepatoblasts differentiate to cholangiocytes, which give rise to the bile ducts. Here, we investigated duct development in mouse liver and characterized the role of the SRY-related HMG box transcription factor 9 (SOX9).Comparative StudyJournal ArticleResearch Support, N.I.H. ExtramuralResearch Support, Non-U.S. Gov'tinfo:eu-repo/semantics/publishe
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