Estimating Global Burden of Disease due to congenital anomaly : An analysis of European data
- Boyle, Breidge
- Addor, Marie-Claude
- Arriola, Larraitz
- Barisic, Ingeborg
- Bianchi, Fabrizio
- Csáky-Szunyogh, Melinda
- de Walle, Hermien E.K.
- Dias, Carlos Matias
- Draper, Elizabeth
- Gatt, Miriam
- Garne, Ester
- Haeusler, Martin
- Källén, Karin
- Latos-Bielenska, Anna
- McDonnell, Bob
- Mullaney, Carmel
- Nelen, Vera
- Neville, Amanda J.
- O'Mahony, Mary
- Queisser-Wahrendorf, Annette
- Randrianaivo-Ranjatoelina, Hanitra
- Rankin, Judith
- Rissmann, Anke
- Ritvanen, Annukka
- Rounding, Catherine
- Tucker, David
- Verellen-Dumoulin, Christine
- Wellesley, Diana
- Wreyford, Ben
- Zymak-Zakutnia, Natalia
- Dolk, Helen
DOIAbstract
Objective To validate the estimates of Global Burden of Disease (GBD) due to congenital anomaly for Europe by comparing infant mortality data collected by EUROCAT registries with the WHO Mortality Database, and by assessing the significance of stillbirths and terminations of pregnancy for fetal anomaly (TOPFA) in the interpretation of infant mortality statistics. Design, setting and outcome measures EUROCAT is a network of congenital anomaly registries collecting data on live births, fetal deaths from 20 weeks' gestation and TOPFA. Data from 29 registries in 19 countries were analysed for 2005-2009, and infant mortality (deaths of live births at age <1 year) compared with the WHO Mortality Database. Eight EUROCAT countries were excluded fro...
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