Deep sequencing analysis of hepatitis B virus quasispecies characteristics in the pre-S region prior to development of hepatocellular carcinoma

Poster Presentations: Viral hepatitis: Hepatitis A, B, D, E – clinical (except therapy): no. THU-111BACKGROUND AND AIMS: Within infected individuals, hepatitis B virus (HBV) exists as quasispecies, defined as the presence a pool of genetically distinct but closely related isolates in a viral population. It is not clear whether there is an association between the evolution of HBV quasispecies and the development of hepatocellular carcinoma (HCC). We aimed to use deep sequencing to examine the dynamic changes of HBV quasispecies and its relationship to HCC development …Link_to_subscribed_fulltex