Naseseazine C, a new anti-plasmodial dimeric diketopiperazine from a marine sediment derived Streptomyces sp.
- Buedenbender, Larissa
- Grkovic, Tanja
- Duffy, Sandra
- Kurtboke, D I
- Avery, Vicky M
- Carroll, Anthony R
DOIAbstract
A new dimeric diketopiperazine, naseseazine C, and the known naseseazines A and B were isolated from solid culture extracts of an Australian marine sediment derived Streptomyces species. Naseseazine C displayed a new C-6′/C-3 linkage between the two diketopiperazine subunits and showed moderate activity against the chloroquine-sensitive malaria parasite, Plasmodium falciparum (3D7 strain)
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