Synthesis of 4-thioacetyl-1,2,3-thiadiazoles. Reversible rearrangement of N-Substituted 5-methyl-1,2,3-thiadiazole-4-carbothioamides

The equilibrium in the reversible rearrangement of 5-methyl-1,2,3- thiadiazole-4-carbothioamides into 5-amino-4-thioacetyl-1,2,3-thiadiazoles is displaced toward the former, and polar solvents favor increased fraction of the thioketone. © Pleiades Publishing, Ltd., 2012