To determine whether MLN8054, an Aurora kinase A (Aurora-A) inhibitor causes radiosensitization in androgen-insensitive prostate cancer cells in vitro and in vivo.Journal ArticleResearch Support, U.S. Gov't, Non-P.H.S.SCOPUS: ar.jinfo:eu-repo/semantics/publishe
Parthenolide (PN), a major active component of the traditional herbal medicine feverfew, has been sh...
Recently, new chemotherapy agents which target the non-structural components of mitosis have been de...
Combining the pan-aurora kinase inhibitor AMG 900 with histone deacetylase inhibitors enhances antit...
Aurora A kinase is critical in assembly and function of the mitotic spindle. It is overexpressed in ...
The Aurora kinases are essential for cell mitosis, and the dysregulation of Aurora A and B have been...
Glioblastoma remains one of the most devastating human malignancies, and despite therapeutic advance...
Aurora Kinase (AK) based therapy targeting AK-A & B is effective against some cancers. We have explo...
Aurora kinases are essential cell cycle regulators for normal cell division. All three members of th...
Title Phase I study of the selective Aurora A kinase inhibitor MLN8054 in patients with advanced sol...
Glioblastoma (GBM) is the most common malignant pri-mary brain tumor. Radiotherapy fails to eliminat...
Recently, new chemotherapy agents which target the non-structural components of mitosis have been de...
Purpose: Deregulated expression of the Aurora kinases (Aurora-A, -B and -C) is thought to be involve...
Radiation therapy is used to treat cancer by radiation-induced DNA damage. Despite the best efforts ...
Aurora kinases are a family of serine/threonine kinases which play an essential role in cell divisio...
8 pagesInternational audienceAurora kinases are serine/threonine protein kinases that are involved i...
Parthenolide (PN), a major active component of the traditional herbal medicine feverfew, has been sh...
Recently, new chemotherapy agents which target the non-structural components of mitosis have been de...
Combining the pan-aurora kinase inhibitor AMG 900 with histone deacetylase inhibitors enhances antit...
Aurora A kinase is critical in assembly and function of the mitotic spindle. It is overexpressed in ...
The Aurora kinases are essential for cell mitosis, and the dysregulation of Aurora A and B have been...
Glioblastoma remains one of the most devastating human malignancies, and despite therapeutic advance...
Aurora Kinase (AK) based therapy targeting AK-A & B is effective against some cancers. We have explo...
Aurora kinases are essential cell cycle regulators for normal cell division. All three members of th...
Title Phase I study of the selective Aurora A kinase inhibitor MLN8054 in patients with advanced sol...
Glioblastoma (GBM) is the most common malignant pri-mary brain tumor. Radiotherapy fails to eliminat...
Recently, new chemotherapy agents which target the non-structural components of mitosis have been de...
Purpose: Deregulated expression of the Aurora kinases (Aurora-A, -B and -C) is thought to be involve...
Radiation therapy is used to treat cancer by radiation-induced DNA damage. Despite the best efforts ...
Aurora kinases are a family of serine/threonine kinases which play an essential role in cell divisio...
8 pagesInternational audienceAurora kinases are serine/threonine protein kinases that are involved i...
Parthenolide (PN), a major active component of the traditional herbal medicine feverfew, has been sh...
Recently, new chemotherapy agents which target the non-structural components of mitosis have been de...
Combining the pan-aurora kinase inhibitor AMG 900 with histone deacetylase inhibitors enhances antit...