Systematic review and meta-analysis of school-based interventions to reduce body mass index

<b>Background</b> Childhood obesity predisposes to adult obesity and increases the risk of many diseases. Schools provide a vehicle to deliver public health interventions to all children.<p></p> <b>Methods</b> Medline and Embase were used to undertake a systematic review of published studies of school-based interventions aimed at reducing the body mass index (BMI) of children ≤ 18 years. Preferred reporting items for systematic reviews and meta-analyses guidelines were followed, and eligible studies subjected to a random effects meta-analysis.<p></p> <b>Results</b> Between 1991 and 2010, 43 published studies provided 60 measurements of effect. The pooled effect was a 0.17 (95% CI: 0.08, 0.26, P< 0.001) reduction in BMI. Heterogeneity was high (I2= 93.4%) but there was no significant small study bias (Egger's test, P= 0.422) nor significant variation by length of follow-up. The intervention comprised physical activity only in 11 (26%) studies, education only in three (7%), and combinations of these and improved nutrition in the remaining 29 (67%). On stratified analysis, physical activity used in isolation (−0.13, 95% CI: −0.22, −0.04, P= 0.001) or combined with improved nutrition (−0.17, 95% CI: −0.29, −0.06, P< 0.001) was associated with significant improvements in BMI. Interventions targeted at overweight/obese children reduced their BMI by 0.35 (95% CI: 0.12, 0.58, P= 0.003). Those delivered to all children reduced it by 0.16 (95% CI: 0.06, 0.25, P= 0.002)<p></p> <b>Conclusions</b> There is growing evidence that school-based interventions that contain a physical activity component may be effective in helping to reduce BMI in children