The DNA Damage Response (DDR) signalling network is an essential system that protects the genome’s integrity. The DDRprot database presented here is a resource that integrates manually curated information on the human DDR network and its sub-pathways. For each particular DDR protein, we present detailed information about its function. If involved in post-translational modifications (PTMs) with each other, we depict the position of the modified residue/s in the three-dimensional structures, when resolved structures are available for the proteins. All this information is linked to the original publication from where it was obtained. Phylogenetic information is also shown, including time of emergence and conservation across 47 selected species...
Maintenance of genome integrity is of importance for prevention of a number of human diseases. The D...
ao ro n DNA damage response (DDR) mechanisms to maintain pathway, non-homologous ends joining (NHEJ)...
textabstractStructural changes to DNA severely affect its functions, such as replication and transcr...
The DNA Damage Response (DDR) signalling network is an essential system that protects the genome's i...
Póster presentado en el XXXVII Congreso de la Sociedad Española de Bioquímica y Biología Molecular (...
The DNA damage response (DDR) is a crucial signaling network that preserves the integrity of the gen...
Trabajo presentado en el XII Symposium on Bioinformatics (XII Jornadas de Bioinformática), celebrado...
Trabajo presentado en el XII Symposium on Bioinformatics (XII Jornadas de Bioinformática), celebrado...
OAK-B135 DNA Damage Recognition and Repair (DDR and R) proteins play a critical role in cellular res...
The DNA damage response (DDR) ensures error-free DNA replication and transcription and is disrupted ...
The DNA Damage response is a crucial signaling network that preserves genome integrity. This networ...
<p>Detailed examination of strains with mutations in DNA-damage-response genes. Each bar graph repre...
All cellular organisms contain genomic DNA which provides the instructions for their correct develop...
markdownabstract__Abstract__ The crucial factor for the survival of an organism resides in geneti...
Abstract DNA-Damage Response (DDR) proteins are crucial for maintaining the integrity of the genome ...
Maintenance of genome integrity is of importance for prevention of a number of human diseases. The D...
ao ro n DNA damage response (DDR) mechanisms to maintain pathway, non-homologous ends joining (NHEJ)...
textabstractStructural changes to DNA severely affect its functions, such as replication and transcr...
The DNA Damage Response (DDR) signalling network is an essential system that protects the genome's i...
Póster presentado en el XXXVII Congreso de la Sociedad Española de Bioquímica y Biología Molecular (...
The DNA damage response (DDR) is a crucial signaling network that preserves the integrity of the gen...
Trabajo presentado en el XII Symposium on Bioinformatics (XII Jornadas de Bioinformática), celebrado...
Trabajo presentado en el XII Symposium on Bioinformatics (XII Jornadas de Bioinformática), celebrado...
OAK-B135 DNA Damage Recognition and Repair (DDR and R) proteins play a critical role in cellular res...
The DNA damage response (DDR) ensures error-free DNA replication and transcription and is disrupted ...
The DNA Damage response is a crucial signaling network that preserves genome integrity. This networ...
<p>Detailed examination of strains with mutations in DNA-damage-response genes. Each bar graph repre...
All cellular organisms contain genomic DNA which provides the instructions for their correct develop...
markdownabstract__Abstract__ The crucial factor for the survival of an organism resides in geneti...
Abstract DNA-Damage Response (DDR) proteins are crucial for maintaining the integrity of the genome ...
Maintenance of genome integrity is of importance for prevention of a number of human diseases. The D...
ao ro n DNA damage response (DDR) mechanisms to maintain pathway, non-homologous ends joining (NHEJ)...
textabstractStructural changes to DNA severely affect its functions, such as replication and transcr...