To access publisher's full text version of this article click on the hyperlink belowObesity is a high risk factor for breast cancer. This relationship could be marked by a specific methylome. The current work was aimed to explore the impact of obesity and menopausal status on variation in breast cancer methylomes. Data from Infinium 450K array-based methylomes of 64 breast tumors were coupled with information on BMI and menopausal status. Additionally, DNA methylation results were validated in 18 non-tumor and 81 tumor breast samples. Breast tumors arising in either pre- or postmenopausal women stratified by BMI or menopausal status alone were not associated with a specific DNA methylation pattern. Intriguingly, the DNA methylation pattern ...
Purpose: Mammographic breast density (MBD) is a marker of increased breast cancer (BC) risk, yet muc...
International audienceBackground: DNA methylation in blood may reflect adverse exposures accumulated...
Background: Obesity is an established risk factor for several common chronic diseases such as breast...
Although obesity is associated with breast cancer incidence and prognosis, the underlying mechanisms...
The methylation levels of ZNF577 in breast tumors has been previously identified as a possible epige...
The methylation levels of ZNF577 in breast tumors has been previously identified as a possible epige...
Mechanisms underlying the poor breast cancer prognosis among obese women are unresolved. DNA methyla...
Epidemiological studies have established obesity as a critical risk factor for postmenopausal breast...
Introduction: Little is known about how modifiable lifestyle factors interact with the epigenome to ...
Aim of the study A vast majority of human malignancies are associated with ageing, and age is a stro...
Gene expression studies indicate that body mass index (BMI) is associated with molecular pathways in...
Globalisation has resulted in several anthropometric, reproductive, and lifestyle factors and/or exp...
A vast majority of human malignancies are associated with ageing, and age is a strong predictor of c...
BACKGROUND: Interest in the potential of DNA methylation in peripheral blood as a biomarker of cance...
Purpose: Mammographic breast density (MBD) is a marker of increased breast cancer (BC) risk, yet muc...
International audienceBackground: DNA methylation in blood may reflect adverse exposures accumulated...
Background: Obesity is an established risk factor for several common chronic diseases such as breast...
Although obesity is associated with breast cancer incidence and prognosis, the underlying mechanisms...
The methylation levels of ZNF577 in breast tumors has been previously identified as a possible epige...
The methylation levels of ZNF577 in breast tumors has been previously identified as a possible epige...
Mechanisms underlying the poor breast cancer prognosis among obese women are unresolved. DNA methyla...
Epidemiological studies have established obesity as a critical risk factor for postmenopausal breast...
Introduction: Little is known about how modifiable lifestyle factors interact with the epigenome to ...
Aim of the study A vast majority of human malignancies are associated with ageing, and age is a stro...
Gene expression studies indicate that body mass index (BMI) is associated with molecular pathways in...
Globalisation has resulted in several anthropometric, reproductive, and lifestyle factors and/or exp...
A vast majority of human malignancies are associated with ageing, and age is a strong predictor of c...
BACKGROUND: Interest in the potential of DNA methylation in peripheral blood as a biomarker of cance...
Purpose: Mammographic breast density (MBD) is a marker of increased breast cancer (BC) risk, yet muc...
International audienceBackground: DNA methylation in blood may reflect adverse exposures accumulated...
Background: Obesity is an established risk factor for several common chronic diseases such as breast...