Background: Genetic Susceptibility may play a more important role in the etiology of early-onset inflammatory bowel disease (IBD) than in late-onset 1131), and therefore pediatric-onset IBD patients can be expected to have a higher frequency of gene mutations. We aimed to determine genotypes and phenotypes of patients with pediatric-onset 113D, to compare them with those of patients with adult-onset]BD and with controls, and to identify genotype-phenotype associations. Methods: Polyinorphisms R702W, G908R, and 3020insC of CARD15 (caspase activating recruitment domain 15); Asp299GIy and Thr3991le of TLR4; -207G -> C, 1672C -> T (L503F), rs3792876, rs274551, rs272893, and rs273900 of SLC22A415; and 113G -> A as well as rs2289311, rsl270912, a...
Item does not contain fulltextBACKGROUND: Crohn's disease and ulcerative colitis have a complex gene...
Inflammatory Bowel disease (IBD) is a widespread pathological condition with clinical heterogeneity ...
BACKGROUND & AIMS: Recent studies reported a role for more than 70 genes or loci in the susceptibili...
Background: Genetic Susceptibility may play a more important role in the etiology of early-onset inf...
<div><p>Background</p><p>The inflammatory bowel diseases (IBD) are common, complex disorders in whic...
The inflammatory bowel diseases (IBD) are common, complex disorders in which genetic and environment...
12Background: Inflammatory bowel diseases (IBDs) are complex, multifactorial disorders that comprise...
OBJECTIVES: Monogenic inflammatory bowel disease (IBD) comprises rare Mendelian causes of gut inflam...
BACKGROUND: Approximately, one-third to one-half of children with chronic granulomatous disease (CGD...
OBJECTIVES: Genetic variants at the CARD15 and IBD5 loci are strongly associated with Crohn's diseas...
Inflammatory bowel disease (IBD) is a common inflammatory disorder with complex etiology that involv...
Objectives: Crohn disease is a chronic inflammatory bowel disorder that is caused by environmental a...
Abstract OBJECTIVES: Recently, genome-wide association analyses have identified single nucleotide p...
BACKGROUND: Crohn's disease and ulcerative colitis are the two major forms of inflammatory bowel dis...
AIM: We investigated the contribution of variants of tumour necrosis factor (TNF)-alpha and MDR1 ge...
Item does not contain fulltextBACKGROUND: Crohn's disease and ulcerative colitis have a complex gene...
Inflammatory Bowel disease (IBD) is a widespread pathological condition with clinical heterogeneity ...
BACKGROUND & AIMS: Recent studies reported a role for more than 70 genes or loci in the susceptibili...
Background: Genetic Susceptibility may play a more important role in the etiology of early-onset inf...
<div><p>Background</p><p>The inflammatory bowel diseases (IBD) are common, complex disorders in whic...
The inflammatory bowel diseases (IBD) are common, complex disorders in which genetic and environment...
12Background: Inflammatory bowel diseases (IBDs) are complex, multifactorial disorders that comprise...
OBJECTIVES: Monogenic inflammatory bowel disease (IBD) comprises rare Mendelian causes of gut inflam...
BACKGROUND: Approximately, one-third to one-half of children with chronic granulomatous disease (CGD...
OBJECTIVES: Genetic variants at the CARD15 and IBD5 loci are strongly associated with Crohn's diseas...
Inflammatory bowel disease (IBD) is a common inflammatory disorder with complex etiology that involv...
Objectives: Crohn disease is a chronic inflammatory bowel disorder that is caused by environmental a...
Abstract OBJECTIVES: Recently, genome-wide association analyses have identified single nucleotide p...
BACKGROUND: Crohn's disease and ulcerative colitis are the two major forms of inflammatory bowel dis...
AIM: We investigated the contribution of variants of tumour necrosis factor (TNF)-alpha and MDR1 ge...
Item does not contain fulltextBACKGROUND: Crohn's disease and ulcerative colitis have a complex gene...
Inflammatory Bowel disease (IBD) is a widespread pathological condition with clinical heterogeneity ...
BACKGROUND & AIMS: Recent studies reported a role for more than 70 genes or loci in the susceptibili...