Association of ambient air pollution with the prevalence and incidence of COPD
- Schikowski, Tamara
- Adam, Martin
- Marcon, Alessandro
- Cai, Yutong
- Vierkötter, Andrea
- Carsin, Anne Elie
- Jacquemin, Benedicte
- Al Kanani, Zaina
- Beelen, Rob
- Birk, Matthias
- Bridevaux, Pierre Olivier
- Brunekreef, Bert
- Burney, Peter
- Cirach, Marta
- Cyrys, Josef
- De Hoogh, Kees
- De Marco, Roberto
- De Nazelle, Audrey
- Declercq, Christophe
- Forsberg, Bertil
- Hardy, Rebecca
- Heinrich, Joachim
- Hoek, Gerard
- Jarvis, Debbie
- Keidel, Dirk
- Kuh, Diane
- Kuhlbusch, Thomas
- Migliore, Enrica
- Mosler, Gioia
- Nieuwenhuijsen, Mark J.
- Phuleria, Harish
- Rochat, Thierry
- Schindler, Christian
- Villani, Simona
- Tsai, Ming Yi
- Zemp, Elisabeth
- Hansell, Anna
- Kauffmann, Francine
- Sunyer, Jordi
- Probst-Hensch, Nicole
- Krämer, Ursula
- Künzli, Nino
DOIAbstract
The role of air pollution in chronic obstructive pulmonary disease (COPD) remains uncertain. The aim was to assess the impact of chronic exposure to air pollution on COPD in four cohorts using the standardised ESCAPE exposure estimates. Annual average particulate matter (PM), nitrogen oxides (NO x) and road traffic exposure were assigned to home addresses using land-use regression models. COPD was defined by NHANES reference equation (forced expiratory volume in 1 s (FEV1)/forced vital capacity (FVC) less than the lower limit of normal) and the Global Initiative for Chronic Obstructive Lung Disease criterion (FEV1/FVC <0.70) and categorised by severity in non-asthmatics. We included 6550 subjects with assigned NOx and 3692 with PM measures....
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