In predisposed individuals, wound healing can lead to hypertrophic scar or keloid formation, characterized by an overabundant extracellular matrix. It has recently been shown that hypertrophic scars are accompanied by abnormal keratinocyte differentiation and proliferation, and significantly increased acanthosis, compared with normal scars. This study addressed the question of whether the development of normal and hypertrophic scars is regulated by differences in the growth factor profiles of both the epidermis and the dermis, The presence of interleukin-l alpha (IL-1 alpha), IL-1 beta, tumour necrosis factor-alpha (TNF-alpha), platelet-derived growth factor (PDGF), transforming growth factor-beta1 (TGF-beta1), and basic fibroblast growth f...
To understand scar pathology, develop new drugs, and provide a platform for personalized medicine, p...
Hypertrophic scar formation is a result of adverse cutaneous wound healing. The pathogenesis of hype...
To understand scar pathology, develop new drugs, and provide a platform for personalized medicine, p...
In predisposed individuals, wound healing can lead to hypertrophic scar or keloid formation, charact...
The role of epidermal keratinocytes in the early phases of normal unimpaired wound healing has been ...
The role of epidermal keratinocytes in the early phases of normal unimpaired wound healing has been ...
The exact pathogenesis of hypertrophic scar and keloid formation is still unknown and a good therapy...
Contains fulltext : 58253schalkwijk.pdf (publisher's version ) (Closed access)The ...
A scar is an expected result of wound healing. However, in some individuals, and particularly in bur...
BACKGROUND: Scar formation is an important component of overall wound health. Defects in scar format...
Keloids and hypertrophic scars are caused by cutaneous injury and irritation, including trauma, inse...
The alteration of normal dermal fibroblast function that leads to the development of hypertrophic sc...
We evaluated the in situ expression of adhesion molecules (E-selectin and vascular cell-adhesion mol...
To understand scar pathology, develop new drugs, and provide a platform for personalized medicine, p...
Hypertrophic scar formation is a result of adverse cutaneous wound healing. The pathogenesis of hype...
To understand scar pathology, develop new drugs, and provide a platform for personalized medicine, p...
In predisposed individuals, wound healing can lead to hypertrophic scar or keloid formation, charact...
The role of epidermal keratinocytes in the early phases of normal unimpaired wound healing has been ...
The role of epidermal keratinocytes in the early phases of normal unimpaired wound healing has been ...
The exact pathogenesis of hypertrophic scar and keloid formation is still unknown and a good therapy...
Contains fulltext : 58253schalkwijk.pdf (publisher's version ) (Closed access)The ...
A scar is an expected result of wound healing. However, in some individuals, and particularly in bur...
BACKGROUND: Scar formation is an important component of overall wound health. Defects in scar format...
Keloids and hypertrophic scars are caused by cutaneous injury and irritation, including trauma, inse...
The alteration of normal dermal fibroblast function that leads to the development of hypertrophic sc...
We evaluated the in situ expression of adhesion molecules (E-selectin and vascular cell-adhesion mol...
To understand scar pathology, develop new drugs, and provide a platform for personalized medicine, p...
Hypertrophic scar formation is a result of adverse cutaneous wound healing. The pathogenesis of hype...
To understand scar pathology, develop new drugs, and provide a platform for personalized medicine, p...