Clinically node negative breast cancer patients undergoing breast conserving therapy, sentinel lymph node procedure versus follow-up: a Dutch randomized controlled multicentre trial (BOOG 2013-08)
- Roozendaal, L.M. van
- Vane, M.L.G.
- Dalen, T. van
- Hage, J.A. van der
- Strobbe, L.J.A.
- Boersma, L.J.
- Linn, S.C.
- Lobbes, M.B.
- Poortmans, P.M.P.
- Tjan-Heijnen, V.C.
- Vijver, K. van der
- Westenberg, A.H.
- Kessels, A.G.
- Wilt, J.H.W. de
- Smidt, M.L.
DOIAbstract
BACKGROUND: Studies showed that axillary lymph node dissection can be safely omitted in presence of positive sentinel lymph node(s) in breast cancer patients treated with breast conserving therapy. Since the outcome of the sentinel lymph node biopsy has no clinical consequence, the value of the procedure itself is being questioned. The aim of the BOOG 2013-08 trial is to investigate whether the sentinel lymph node biopsy can be safely omitted in clinically node negative breast cancer patients treated with breast conserving therapy. METHODS: The BOOG 2013-08 is a Dutch prospective non-inferiority randomized multicentre trial. Women with pathologically confirmed clinically node negative T1-2 invasive breast cancer undergoing breast conserving...
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